DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8026 and SPBC27B12.09c

DIOPT Version :9

Sequence 1:	NP_724769.2	Gene:	CG8026 / 35941	FlyBaseID:	FBgn0033391	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_595541.1	Gene:	SPBC27B12.09c / 2540370	PomBaseID:	SPBC27B12.09c	Length:	277	Species:	Schizosaccharomyces pombe

Alignment Length:	292	Identity:	108/292 - (36%)
Similarity:	150/292 - (51%)	Gaps:	34/292 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EHLVAGVSGGVVSTLILHPLDLIKIRFAVNDGRTATVPQYRGLSSAFTTIFRQEG-FRGLYKGVT 87
            :..:||::.|..||||:|||||.||:...:..:.:     :.|...|.:.....| .|.||.|::
pombe     2 DQAIAGLAAGTASTLIMHPLDLAKIQMQASMNQDS-----KSLFQVFKSNIGSNGSIRSLYHGLS 61

  Fly    88 PNVWGSGSSWGLYFMFYNTIKTFIQGGNTTMPLGPTMN--------MLAAAESGILTLLLTNPIW 144
            .||.||.:|||.||..|:..|..:      |.:.|..|        :.::..:|.:...||||||
pombe    62 INVLGSAASWGAYFCIYDFSKRVV------MSMTPFNNGEISVLQTLCSSGFAGCIVAALTNPIW 120

  Fly   145 VVKTRLCLQCDAASSAEYRGMIHALGQIYKEEGIRGLYRGFVPGMLGVSHGAIQFMTYEELKNAY 209
            |||:|:     .:....|.........:.|.||:||.|.||.|.:||||.||:|||.||:|| .:
pombe   121 VVKSRI-----LSKRVNYTNPFFGFYDLIKNEGLRGCYAGFAPSLLGVSQGALQFMAYEKLK-LW 179

  Fly   210 NEYRKLPIDTKLATTEYLAFAAVSKLIAAAATYPYQVVRARLQDHHHRYNGTWDCIKQTWRFEGY 274
            .:.|...:|       |:..:|.||:.||...||..|:|.|||.....:....:.:.||||.:|.
pombe   180 KQRRPTSLD-------YIFMSAASKVFAAVNMYPLLVIRTRLQVMRSPHRSIMNLVLQTWRLQGI 237

  Fly   275 RGFYKGLKASLTRVVPACMVTFLVYENVS-HF 305
            .|||||....|.||||...:||||||.|. ||
pombe   238 LGFYKGFLPHLLRVVPQTCITFLVYEQVGMHF 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8026	NP_724769.2	PTZ00169	13..287	CDD:240302	95/271 (35%)
		Mito_carr	23..115	CDD:278578	32/91 (35%)
		Mito_carr	119..213	CDD:278578	36/101 (36%)
		Mito_carr	220..307	CDD:278578	37/87 (43%)
SPBC27B12.09c	NP_595541.1	PTZ00169	2..250	CDD:240302	95/271 (35%)
		Mito_carr	5..88	CDD:278578	33/93 (35%)
		Mito_carr	94..183	CDD:278578	34/94 (36%)
		Mito_carr	183..265	CDD:278578	36/88 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	72	1.000	Domainoid score	I2607
eggNOG	1	0.900	-	-		E1_KOG0764
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6151
Inparanoid	1	1.050	175	1.000	Inparanoid score	I1160
OMA	1	1.010	-	-		QHG53601
OrthoFinder	1	1.000	-	-		FOG0002021
OrthoInspector	1	1.000	-	-		oto100893
orthoMCL	1	0.900	-	-		OOG6_100767
Panther	1	1.100	-	-	LDO	PTHR45683
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1725
SonicParanoid	1	1.000	-	-		X1155
TreeFam	1	0.960	-	-
	14	13.860