Protein Alignment CG8026 and SLC25A25

DIOPT Version :10

• Sequence 1: NP_724769.2
• Gene: CG8026 / 35941
• FlyBaseID: FBgn0033391
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_001317917.1
• Gene: SLC25A25 / 114789
• HGNCID: 20663
• Length: 515
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 86/287 - (29%)
• Similarity: 135/287 - (47%)
• Gaps: 20/287 - (6%)

  Fly    23 YEHLVAGVSGGVVSTLILHPLDLIKIRFAVNDGRTATVPQYRGLSSAFTTIFRQEGFRGLYKGVT 87
            :.|||||...|.||.....|||.:|:...|:..|:..:    |:...||.:.|:.|.|.|::|..
Human   233 WRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNM----GIVGGFTQMIREGGARSLWRGNG 293

  Fly    88 PNVWGSGSSWGLYFMFYNTIKTFIQGGNTTMPLGPTMNMLAAAESGILTLLLTNPIWVVKTRLCL 152
            .||........:.||.|..||..:.....|:.:..  .::|.:.:|.:......|:.|:|||:.|
Human   294 INVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHE--RLVAGSLAGAIAQSSIYPMEVLKTRMAL 356

  Fly   153 QCDAASSAEYRGMIHALGQIYKEEGIRGLYRGFVPGMLG-VSHGAIQFMTYEELKNAY-NEYRKL 215
            :    .:.:|.||:....:|...||:...|:|:||.||| :.:..|....||.||||: ..|...
Human   357 R----KTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVN 417

  Fly   216 PIDTKLATTEYLAFAAVSKLIAAAATYPYQVVRARLQDHHHRYNGTWD-----CIKQTWRFEGYR 275
            ..|..:..  .||...:|......|:||..:||.|:| ......|..:     ..|...|.||..
Human   418 SADPGVFV--LLACGTMSSTCGQLASYPLALVRTRMQ-AQASIEGAPEVTMSSLFKHILRTEGAF 479

  Fly   276 GFYKGLKASLTRVVPACMVTFLVYENV 302
            |.|:||..:..:|:||..::::||||:
Human   480 GLYRGLAPNFMKVIPAVSISYVVYENL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8026	NP_724769.2	Mito_carr	23..115	CDD:395101	29/91 (32%)
		Mito_carr	119..213	CDD:395101	28/95 (29%)
		Mito_carr	220..307	CDD:395101	26/88 (30%)
SLC25A25	NP_001317917.1	FRQ1	49..189	CDD:444056
		PTZ00169	237..491	CDD:240302	77/266 (29%)