DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab32 and RAB5A

DIOPT Version :9

Sequence 1:	NP_525109.1	Gene:	Rab32 / 35940	FlyBaseID:	FBgn0002567	Length:	686	Species:	Drosophila melanogaster
Sequence 2:	NP_004153.2	Gene:	RAB5A / 5868	HGNCID:	9783	Length:	215	Species:	Homo sapiens

Alignment Length:	174	Identity:	54/174 - (31%)
Similarity:	94/174 - (54%)	Gaps:	11/174 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 YKILVIGELGTGKTSFIKRYVHQFFSQNYRATIGVDFALKVLQWDANTIVRLQLWDIAGQERFGN 548
            :|::::||...||:|.:.|:|...|.:...:|||..|..:.:..| :|.|:.::||.|||||:.:
Human    21 FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLD-DTTVKFEIWDTAGQERYHS 84

  Fly   549 MTRVYYKEAVGAFIVFDVTRSGTFDCVSKWKEDLDSKVQLPDGSP-IPCILLANKCD-QEKQGII 611
            :..:||:.|..|.:|:|:|...:|.....|.::|..:     .|| |...|..||.| ..|:.:.
Human    85 LAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQ-----ASPNIVIALSGNKADLANKRAVD 144

  Fly   612 TQPEKMDEYVRENGFAGWFETSAKENINIDEAARALVNKILIND 655
            .|  :...|..:|... :.|||||.::|::|...|:..|:..|:
Human   145 FQ--EAQSYADDNSLL-FMETSAKTSMNVNEIFMAIAKKLPKNE 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab32	NP_525109.1	Rab32_Rab38	484..686	CDD:206692	54/174 (31%)
Rab32	NP_525109.1	RAB	484..652	CDD:197555	53/169 (31%)
RAB5A	NP_004153.2	Rab5_related	20..182	CDD:206653	53/169 (31%)
		Effector region. /evidence=ECO:0000255	49..57		3/7 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..215		1/5 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1340129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010