DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rab32 and RAB22A

DIOPT Version :9

Sequence 1:NP_525109.1 Gene:Rab32 / 35940 FlyBaseID:FBgn0002567 Length:686 Species:Drosophila melanogaster
Sequence 2:NP_065724.1 Gene:RAB22A / 57403 HGNCID:9764 Length:194 Species:Homo sapiens


Alignment Length:205 Identity:67/205 - (32%)
Similarity:100/205 - (48%) Gaps:23/205 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly   485 KILVIGELGTGKTSFIKRYVHQFFSQNYRATIGVDFALKVLQWDANTIVRLQLWDIAGQERFGNM 549
            |:.::|:.|.||:|.:.|:|...|..|...|||..|..|.:|:. |.:.:..:||.||||||..:
Human     7 KVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQ-NELHKFLIWDTAGQERFRAL 70

  Fly   550 TRVYYKEAVGAFIVFDVTRSGTFDCVSKWKEDLDSKVQLPDGSP-IPCILLANKCDQEKQGIITQ 613
            ..:||:.:..|.||:|:|:..||..:..|.::|..     .|.| |...:..||||     :|..
Human    71 APMYYRGSAAAIIVYDITKEETFSTLKNWVKELRQ-----HGPPNIVVAIAGNKCD-----LIDV 125

  Fly   614 PEKMDEYVRENG---FAGWFETSAKENINIDEAARALVNKILINDKLISADLADGDK-FNLSAAD 674
            .|.|:...::..   .|.:.|||||..|||:|....:..:|...|    |:|..|.| |.|....
Human   126 REVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPSTD----ANLPSGGKGFKLRRQP 186

  Fly   675 ATGSDAKNKC 684
               |:.|..|
Human   187 ---SEPKRSC 193

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab32NP_525109.1 Rab32_Rab38 484..686 CDD:206692 67/205 (33%)
RAB 484..652 CDD:197555 56/170 (33%)
RAB22ANP_065724.1 Rab5_related 5..167 CDD:206653 56/170 (33%)
Ras 7..167 CDD:278499 56/170 (33%)
Effector region. /evidence=ECO:0000250 34..42 3/7 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 174..194 7/23 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1340129at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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