Protein Alignment Rab32 and RAB19

DIOPT Version :10

• Sequence 1: NP_525109.1
• Gene: Rab32 / 35940
• FlyBaseID: FBgn0002567
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_001008749.2
• Gene: RAB19 / 401409
• HGNCID: 19982
• Length: 217
• Species: Homo sapiens
• Alignment Length: 218
• Identity: 67/218 - (30%)
• Similarity: 110/218 - (50%)
• Gaps: 27/218 - (12%)

  Fly   481 EHLYKILVIGELGTGKTSFIKRYVHQFFSQNYRATIGVDFALKVLQWDANTIVRLQLWDIAGQER 545
            ::|:||::||:...|||..::.:....:::..:.||||||.::.|..|... |::|:||.|||||
Human    15 DYLFKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGKK-VKMQVWDTAGQER 78

  Fly   546 FGNMTRVYYKEAVGAFIVFDVTRSGTFDCVSKWKEDLDSKVQLPDGSPIPCILLANKCD-QEKQG 609
            |..:|:.||:.|..|.|.:|:||..||:.:..|..:::..    ..:.:..:|:.|||| .||:.
Human    79 FRTITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKY----GAANVVIMLIGNKCDLWEKRH 139

  Fly   610 II-----TQPEKMDEYVRENGFAGWFETSAKENINIDEAARALVNKILINDKLISADLADGDKFN 669
            ::     |..||.       |.....||||||:.||:|....:..:::..:.|   .|......|
Human   140 VLFEDACTLAEKY-------GLLAVLETSAKESKNIEEVFVLMAKELIARNSL---HLYGESALN 194

  Fly   670 LSAAD------ATGSDAKNKCSC 686
            ....|      |.|...|..|:|
Human   195 GLPLDSSPVLMAQGPSEKTHCTC 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab32	NP_525109.1	PHA03247	<126..481	CDD:223021	67/218 (31%)
		Rab32_Rab38	484..686	CDD:206692	65/213 (31%)
RAB19	NP_001008749.2	Rab19	15..179	CDD:133267	58/175 (33%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H0U4	39..54		4/14 (29%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H0U4	74..89		9/14 (64%)