Protein Alignment Rab32 and RAB32

DIOPT Version :9

• Sequence 1: NP_525109.1
• Gene: Rab32 / 35940
• FlyBaseID: FBgn0002567
• Length: 686
• Species: Drosophila melanogaster
• Sequence 2: NP_006825.1
• Gene: RAB32 / 10981
• HGNCID: 9772
• Length: 225
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 146/227 - (64%)
• Similarity: 171/227 - (75%)
• Gaps: 9/227 - (3%)

  Fly   460 GDLTMDQEMEPAIMTSTSDKREHLYKILVIGELGTGKTSFIKRYVHQFFSQNYRATIGVDFALKV 524
            ||..:.....||     .:.||||:|:|||||||.||||.|||||||.|||:|||||||||||||
Human     7 GDPGLGAAAAPA-----PETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKV 66

  Fly   525 LQWDANTIVRLQLWDIAGQERFGNMTRVYYKEAVGAFIVFDVTRSGTFDCVSKWKEDLDSKVQLP 589
            |.||:.|:|||||||||||||||||||||||||||||:|||::||.||:.|.|||.||||||.||
Human    67 LNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLP 131

  Fly   590 DGSPIPCILLANKCDQEKQGIITQPEKMDEYVRENGFAGWFETSAKENINIDEAARALVNKILIN 654
            :|||||.:||||||||.|.. ...|.::|::.:|:|||||||||||:||||:||||.||.|||:|
Human   132 NGSPIPAVLLANKCDQNKDS-SQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVN 195

  Fly   655 DKLISADLADGDKFNLSAADATGSDAKNKCSC 686
            .:....:..|.||..|   |.....|:||..|
Human   196 HQSFPNEENDVDKIKL---DQETLRAENKSQC 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab32	NP_525109.1	Rab32_Rab38	484..686	CDD:206692	137/201 (68%)
		RAB	484..652	CDD:197555	126/167 (75%)
RAB32	NP_006825.1	Rab32_Rab38	26..224	CDD:206692	137/201 (68%)
		Effector region. /evidence=ECO:0000250	54..62		7/7 (100%)
		PKA-RII subunit binding domain	178..197		14/18 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	267	1.000	Domainoid score	I1883
eggNOG	1	0.900	-	-		E1_KOG4423
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H38233
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001263
OrthoInspector	1	1.000	-	-		oto90977
orthoMCL	1	0.900	-	-		OOG6_103102
Panther	1	1.100	-	-	LDO	PTHR24073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3110
SonicParanoid	1	1.000	-	-		X1523
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.800