DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rme-8 and CG7872

DIOPT Version :9

Sequence 1:	NP_610467.1	Gene:	Rme-8 / 35939	FlyBaseID:	FBgn0015477	Length:	2408	Species:	Drosophila melanogaster
Sequence 2:	NP_573044.1	Gene:	CG7872 / 32493	FlyBaseID:	FBgn0030658	Length:	333	Species:	Drosophila melanogaster

Alignment Length:	153	Identity:	38/153 - (24%)
Similarity:	59/153 - (38%)	Gaps:	45/153 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1301 QQAYQDLGIDLTKTPKPDESMIRKSYYKLAQMYHPDKNPNGREI-------FEKVNQAYEFLC-- 1356
            :..|..||:    |.:..:|.|.|:|.:||:.||||.: .|.|.       |:.|..|||.|.
  Fly    30 ENCYDVLGV----TRESSKSEIGKAYRQLARRYHPDLH-RGAEAKAAAETQFKLVATAYEILRDE 89

  Fly  1357 -SRNVWSSGGPDPNN----------------------IVLILRTQSIL-----FERYPDVLRPYK 1393
             ||..:.....:|:.                      ||::|...|::     ::||...:   |
  Fly    90 ESRTDYDYMLDNPDAYYAHYYRYYRRRVAPKVDVRVVIVVVLTIVSVIQYYSGWQRYDSAI---K 151

  Fly  1394 YAGYPQLIKTIRLETRDDELFSK 1416
            |.......:...||...||:..|
  Fly   152 YFATVPKYRNQALEIARDEIQEK 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rme-8	NP_610467.1	DUF4339	972..1020	CDD:290937
		DnaJ	1304..1356	CDD:278647	21/58 (36%)
		HEAT repeat	2174..2200	CDD:293787
		HEAT repeat	2212..2243	CDD:293787
		HEAT repeat	2253..2282	CDD:293787
		HEAT repeat	2291..2327	CDD:293787
CG7872	NP_573044.1	DnaJ	31..96	CDD:278647	24/69 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464439
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930