DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rad51D and RAD57

DIOPT Version :9

Sequence 1:	NP_610466.2	Gene:	Rad51D / 35937	FlyBaseID:	FBgn0033389	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_010287.1	Gene:	RAD57 / 851567	SGDID:	S000002411	Length:	460	Species:	Saccharomyces cerevisiae

Alignment Length:	243	Identity:	64/243 - (26%)
Similarity:	109/243 - (44%)	Gaps:	38/243 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 YQLNLLRKNNICSLIDFYDADEKKLHELWAINIQSV---REL------KKELSLLPKGSV--DEG 72
            |.|:.:|:|.:| ::||.....|:|..|...:|..|   ::|      :|.|.:..|.|:  |.|
Yeast    33 YLLDAVRQNGVC-VVDFLTLTPKELARLIQRSINEVFRFQQLLVHEYNEKYLEICEKNSISPDNG 96

  Fly    73 TPDFNYDTGIEELDKLLDSVEQPFKPGRVWELCGQPGVGKTQLLYTLALNFVWKHSQAVL----- 132
            ...|.  |....:|:||..  ..|..| :.|:.|:...||:|||..|||:.........|
Yeast    97 PECFT--TADVAMDELLGG--GIFTHG-ITEIFGESSTGKSQLLMQLALSVQLSEPAGGLGGKCV 156

  Fly   133 FIDTKREFSCKRIQDMLRAREVDEEASERAMKGIRVVQAATGADINDLLKSFDHQLTAETHASMQ 197
            :|.|:.:...:|::.||.:|...|:.      ||......| ...|||:.. :|.:..:....::
Yeast   157 YITTEGDLPTQRLESMLSSRPAYEKL------GITQSNIFT-VSCNDLINQ-EHIINVQLPILLE 213

  Fly   198 -----TKLVLIDSLAACFAF-YRGRRMRDVR--KSVLTELACKIRKLA 237
                 .|||:|||::..... .:.:..|:.:  |:.|..:|.|::.||
Yeast   214 RSKGSIKLVIIDSISHHLRVELQNKSFRESQENKNYLDRMAEKLQILA 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rad51D	NP_610466.2	P-loop_NTPase	80..336	CDD:304359	44/171 (26%)
Rad51D	NP_610466.2	radB	80..335	CDD:236482	44/171 (26%)
RAD57	NP_010287.1	XRCC3	107..445	CDD:410899	43/166 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346036
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.700