Protein Alignment Rad51D and XRCC3

DIOPT Version :9

• Sequence 1: NP_610466.2
• Gene: Rad51D / 35937
• FlyBaseID: FBgn0033389
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001093588.1
• Gene: XRCC3 / 7517
• HGNCID: 12830
• Length: 346
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 86/373 - (23%)
• Similarity: 145/373 - (38%)
• Gaps: 79/373 - (21%)

  Fly     1 MDLRPMILQTCTGRLLSEYQLNLLRKNNICSLIDFYDADEKKL-----HELWAI----------- 49
            :||.|.|:..          :...:..::..::.|...|.|:|     .|:|.:
Human     6 LDLNPRIIAA----------IKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGS 60

  Fly    50 NIQSVRELKKELSLLPKGSVDEGTPDFNYDTGIEELDKL------LDSVEQPFKPGRVWELCGQP 108
            :|.:..:|.::....|       |.......|...||.|      ||.:.         ||.|:.
Human    61 SILTALQLHQQKERFP-------TQHQRLSLGCPVLDALLRGGLPLDGIT---------ELAGRS 109

  Fly   109 GVGKTQLL--YTLALNFVWKH---SQAVLFIDTKREFSCKRIQDML----RAR-EVDEEASERAM 163
            ..|||||.  ..||:.|..:|   ....::|.|:..|..||:|.::    |.| :|..|..::..
Human   110 SAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLR 174

  Fly   164 KGIRVVQAATGADINDLLKSFDHQLTAETHASMQTKLVLIDSLAACFAFYRGRRMRDVRKSVLTE 228
            .|.::..... ||::.||:..:.::.......| .:||:|||:||.|......:....|...|..
Human   175 FGSQIFIEHV-ADVDTLLECVNKKVPVLLSRGM-ARLVVIDSVAAPFRCEFDSQASAPRARHLQS 237

  Fly   229 LACKIRKL--ALRGVAFVIGNVSFFENNKDSCGDDGEQNGD----DEEVTRQQLEPMLGSYWSSV 287
            |...:|:|  |.:.....|..|:      ::..:.|..:|.    ||.|:     |.||..|::.
Human   238 LGATLRELSSAFQSPVLCINQVT------EAMEEQGAAHGPLGFWDERVS-----PALGITWANQ 291

  Fly   288 ATLRLSVELPEEEDFTLQDDGLRFIYVISNTYGPDGEHCLLRITDAGV 335
            ..:||..:...||:..|.... |.:.|:|..:.|... |...|:..||
Human   292 LLVRLLADRLREEEAALGCPA-RTLRVLSAPHLPPSS-CSYTISAEGV 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rad51D	NP_610466.2	P-loop_NTPase	80..336	CDD:304359	72/278 (26%)
		radB	80..335	CDD:236482	70/276 (25%)
XRCC3	NP_001093588.1	Rad51_DMC1_radA	82..338	CDD:238543	72/280 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158705
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740