Protein Alignment Rad51D and RAD51C

DIOPT Version :10

• Sequence 1: NP_610466.2
• Gene: Rad51D / 35937
• FlyBaseID: FBgn0033389
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: XP_006722064.1
• Gene: RAD51C / 5889
• HGNCID: 9820
• Length: 377
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 61/269 - (22%)
• Similarity: 99/269 - (36%)
• Gaps: 91/269 - (33%)

  Fly   103 ELCGQPGVGKTQLLYTLALN------FVWKHSQAVLFIDTKREFSCKRIQDMLRAREVDEEASER 161
            |:||.||||||||...||::      |.....:|| ||||:..|...|:.|:..|
Human   122 EICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAV-FIDTEGSFMVDRVVDLATA---------- 175

  Fly   162 AMKGIRVVQAATGADINDLLKSFDH-QLTAETHASMQTKLVL----IDSLAACFAFYRGRRMRDV 221
                                 ...| ||.||.|...:.:..|    :|::.:...::|.|...::
Human   176 ---------------------CIQHLQLIAEKHKGEEHRKALEDFTLDNILSHIYYFRCRDYTEL 219

  Fly   222 RKSV------LTELACKIRKLALRGVAFVIGN-------------------VSFFENNKDSCGDD 261
            ...|      |:|.: |:|.:.:.|:||...:                   :|...|::.:....
Human   220 LAQVYLLPDFLSEHS-KVRLVIVDGIAFPFRHDLDDLSLRTRLLNGLAQQMISLANNHRLAVILT 283

  Fly   262 GEQNGDDEEVTRQQ--LEPMLGSYWSSVATLRL-------------SVELPEEED----FTLQDD 307
            .:..   .::.|.|  |.|.||..|...||:||             ..:.|.:::    |.::..
Human   284 NQMT---TKIDRNQALLVPALGESWGHAATIRLIFHWDRKQSRLATLYKSPSQKECTVLFQIKPQ 345

  Fly   308 GLRFIYVIS 316
            |.|...|.|
Human   346 GFRDTVVTS 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rad51D	NP_610466.2	P-loop containing Nucleoside Triphosphate Hydrolases	94..300	CDD:476819	56/247 (23%)
RAD51C	XP_006722064.1	Rad51C	118..331	CDD:410900	55/244 (23%)