Protein Alignment Rad51D and Rad51

DIOPT Version :9

• Sequence 1: NP_610466.2
• Gene: Rad51D / 35937
• FlyBaseID: FBgn0033389
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_035364.1
• Gene: Rad51 / 19361
• MGIID: 97890
• Length: 339
• Species: Mus musculus
• Alignment Length: 343
• Identity: 80/343 - (23%)
• Similarity: 124/343 - (36%)
• Gaps: 117/343 - (34%)

  Fly    39 DEKKLHELW--------------AINIQSVRELKKE------LSLLPKGSVDEGTPDFN------ 77
            |.|||.|..              .|||:.:.|.|.:      ..|:|.|...  ..:|:
Mouse    37 DVKKLEEAGYHTVEAVAYAPKKELINIKGISEAKADKILTEAAKLVPMGFTT--ATEFHQRRSEI 99

  Fly    78 --YDTGIEELDKLLDSVEQPFKPGRVWELCGQPGVGKTQLLYTLALNFVWKHSQA-----VLFID 135
              ..||.:||||||   :...:.|.:.|:.|:...||||:.:|||:.......:.     .::||
Mouse   100 IQITTGSKELDKLL---QGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYID 161

  Fly   136 TKREFSCKRIQDMLRAREVDEEASERAMKGIRVVQAATGADIND---LLKSF--DH--QLTAETH 193
            |:..|..:|:.          ..:||        ...:|:|:.|   ..:.|  ||  ||..:..
Mouse   162 TEGTFRPERLL----------AVAER--------YGLSGSDVLDNVAYARGFNTDHQTQLLYQAS 208

  Fly   194 ASM---QTKLVLIDSLAACF-AFYRGRRMRDVRKSVLTELACKIRKLALR-GVAFVIGNVSFFEN 253
            |.|   :..|:::||..|.: ..|.||.....|:..|......:.:||.. |||.||.|
Mouse   209 AMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITN------ 267

  Fly   254 NKDSCGDDGEQNGDDEEVTRQ----------QLEPMLGSYWSSVATLRLSVE------------- 295
                            :|..|          ..:|:.|:..:..:|.||.:.
Mouse   268 ----------------QVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYD 316

  Fly   296 ---LPEEED-FTLQDDGL 309
               |||.|. |.:..||:
Mouse   317 SPCLPEAEAMFAINADGV 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rad51D	NP_610466.2	P-loop_NTPase	80..336	CDD:304359	66/274 (24%)
		radB	80..335	CDD:236482	66/274 (24%)
Rad51	NP_035364.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		recomb_RAD51	25..339	CDD:274048	80/343 (23%)
		Interaction with PALB2. /evidence=ECO:0000250	184..257		19/72 (26%)
		Nuclear export signal, masked by the interaction with BRCA2. /evidence=ECO:0000250|UniProtKB:Q06609	245..260		3/14 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810