DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rad51D and rad-51

DIOPT Version :9

Sequence 1:	NP_610466.2	Gene:	Rad51D / 35937	FlyBaseID:	FBgn0033389	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001023465.1	Gene:	rad-51 / 177914	WormBaseID:	WBGene00004297	Length:	395	Species:	Caenorhabditis elegans

Alignment Length:	257	Identity:	65/257 - (25%)
Similarity:	99/257 - (38%)	Gaps:	52/257 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 TGIEELDKLLDSVEQPFKPGRVWELCGQPGVGKTQLLYTLALNFVWKHSQAVL------------ 132
            ||...||:||..   ..:.|.:.|:.|:...|||||.          ||.|||
Worm   158 TGSASLDRLLGG---GIETGSITEVYGEYRTGKTQLC----------HSLAVLCQLPIDMGGGEG 209

  Fly   133 ---FIDTKREFSCKRIQDMLRAREVDEEASERAMKGIRVVQAATGADINDLLKSFDHQLTAETHA 194
               :|||...|..:||..:.:...:|   |...::.|.|.:|.....:..|:......::...:|
Worm   210 KCMYIDTNATFRPERIIAIAQRYNMD---SAHVLENIAVARAYNSEHLMALIIRAGAMMSESRYA 271

  Fly   195 SMQTKLVLIDSLAACFA-FYRGRRMRDVRKSVLTELACKIRKLALR-GVAFVI---------GNV 248
                 :|::|...|.|. .|.||.....|:..|:.....:.|||.. |||.:|         |..
Worm   272 -----VVIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYGVAVIITNQVVAQVDGGA 331

  Fly   249 SFFENNKDSCGDDGEQNGDDEEVTRQQLEPMLGSYWSSVATLRLSVELPE-EEDFTLQDDGL 309
            |.|:  .|:....|.........||..|....|.  :.||.:..|..||| |..:::.:.|:
Worm   332 SMFQ--ADAKKPIGGHIIAHMSTTRLYLRKGKGE--NRVAKMVQSPNLPEAEATYSITNHGI 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rad51D	NP_610466.2	P-loop_NTPase	80..336	CDD:304359	65/257 (25%)
Rad51D	NP_610466.2	radB	80..335	CDD:236482	65/257 (25%)
rad-51	NP_001023465.1	PTZ00035	62..394	CDD:185407	65/257 (25%)
		HHH_5	<94..132	CDD:291205
		Rad51_DMC1_radA	156..390	CDD:238543	65/257 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910