Protein Alignment CG8046 and Slc46a3

DIOPT Version :9

• Sequence 1: NP_724761.1
• Gene: CG8046 / 35936
• FlyBaseID: FBgn0033388
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001343931.1
• Gene: Slc46a3 / 71706
• MGIID: 1918956
• Length: 460
• Species: Mus musculus
• Alignment Length: 493
• Identity: 99/493 - (20%)
• Similarity: 191/493 - (38%)
• Gaps: 87/493 - (17%)

  Fly    64 LEPFILILLFAYNFSSTVLKNEVIYQSC---TAGFGYPD----SVCQLLGTKNITNETKRIEEQV 121
            :||.||:..||... :..|..:.:|:..   |..:.:..    |.|.    :|.::......|:|
Mouse     6 IEPAILLNAFAMTL-TIPLTAQYVYRRIWEETGNYTFASNSNGSECD----QNKSSSIFAFREEV 65

  Fly   122 QPYAAQVTLAMRLVECFIPAFCGLF---AGSWADHYGRK-PLLMCSFLGYGLQYLISAAIAYCAM 182
            |..|:...|.:.: ...||.....|   |.|  |::||| |:::.|....|
Mouse    66 QKKASLFNLQVEM-SALIPGLVSTFMLLASS--DNHGRKLPMVLSSLGSLG-------------- 113

  Fly   183 YTQGLVSPWWYVLSI--VPLSCL----------GSSVTYSVAAVCFIADVSGGKVRSYRMIA--- 232
                 .:.|..::|.  :||..|          |:..|:..|...:|.|..  |...:|:|.
Mouse   114 -----TNTWLCMMSYFDLPLQLLIASTFIGALFGNYTTFWGACFAYIVDQQ--KEYKHRIIRIAI 171

  Fly   233 --YELAIYVGLLLGSLGSGYAYEATDAYIVFSISAVCIFTALFLMALLLPESLPARNRTLSTPTT 295
              :.|.:..||.  .|.|||..........:.|:|:.:...|..:...|.:.:    :..|:...
Mouse   172 LDFMLGVVTGLT--GLSSGYFIRELGFVWSYFITAMVLIVNLAYILFFLNDPI----KESSSQIV 230

  Fly   296 DTSVVSMLKSLW---STCSKPREHQNRFMLTTIMVVLLLTAFVSDGSNSVFYKF-MRIKFHWTVK 356
            ..|.:..||.|:   ....|....:.:.:|..::..|::..||..|.:.:|..: :.....|.
Mouse   231 TMSCIESLKDLFYRTYMLFKNGSSKRQALLCLLIFTLVIYFFVIIGISPIFTLYELGPPLCWN-- 293

  Fly   357 QFTEYETVGILVPAVAGSGGVLFIWSLRKCTNSAILWLALVSLLSHCSSSLMKGFALESWQIYVA 421
              ..|...|..:.:|:.....|.||....|...  :.:|.:.:.:......:..|...:..:::.
Mouse   294 --EVYIGYGSALGSVSFLSSFLGIWLFSYCLKD--IHIAYIGIFTTMVGMTLAAFTRTTLMMFLV 354

  Fly   422 IGLGVFKSLVNPMCRTMITNLLPADERGKIFALLGVLQALSPLISSTLYVAIYTRTLNTEPGIFN 486
            ....:|..:...:.|:|::.::.:.|:|.:||.:..|:.|:.:.|::.|..||:.|:...||..
Mouse   355 RIPFIFTIMPLSVLRSMLSKVVHSTEQGALFACIAFLETLAGVTSTSAYSGIYSATVAWYPGFI- 418

  Fly   487 VFSAFLFGIGIILLGTV---------WHKKSRNLVYYE 515
                ||...|:::|..:         |.:.|..|:.:|
Mouse   419 ----FLLSAGLLVLPAISLCCVKSIGWEEGSYTLLVHE 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8046	NP_724761.1	MFS_1	138..467	CDD:284993	67/353 (19%)
		MFS	141..503	CDD:119392	76/386 (20%)
Slc46a3	NP_001343931.1	MFS	3..437	CDD:391944	95/476 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I9497
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	122	1.000	Inparanoid score	I4732
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8701
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.980