Protein Alignment CG8046 and SLC46A2

DIOPT Version :9

• Sequence 1: NP_724761.1
• Gene: CG8046 / 35936
• FlyBaseID: FBgn0033388
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_149040.3
• Gene: SLC46A2 / 57864
• HGNCID: 16055
• Length: 475
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 103/440 - (23%)
• Similarity: 180/440 - (40%)
• Gaps: 63/440 - (14%)

  Fly   106 GTKNITNETK------RIEEQVQPYAAQVTLAMRLVECFIPAFCGLFAGSWADHYGRKPLLMCSF 164
            ||...:|.:.      .:|:|.|...:...:...||....|.......|..:|.|.||..:..|.
Human    49 GTGGSSNHSASPSPRGALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSL 113

  Fly   165 LGYGLQYL---------ISAAIAYCAMYTQGL---VSPWWYVLSIVPLSCLGSSVTYSVAAVCFI 217
            ||:.|..|         ....:.|.|....||   .|.:|  ..::.|..|||
Human   114 LGFLLSRLGLLLKVLLDWPVEVLYGAAALNGLFGGFSAFW--SGVMALGSLGS------------ 164

  Fly   218 ADVSGGKVRSYRMIAYELAIYVGLLLGSLGSGYAYE-----ATDAYIVFSISAVCIFTALF--LM 275
               |.|: ||.|:|..:|.:.:....||:.||:.::     :....|:.:.|..|...||.  |:
Human   165 ---SEGR-RSVRLILIDLMLGLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLL 225

  Fly   276 ALLLPESLPARNRTLSTPTTDTSVVSMLKSL--------WSTCSKPREHQNRFMLTTIMVVLLLT 332
            .|.:|||:...::.|....|.:..|...::|        ::....|...:.:...||| .:|.:.
Human   226 VLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPDQLDQQYAVGHPPSPGKAKPHKTTI-ALLFVG 289

  Fly   333 AFVSD----GSNSVFYKF-MRIKFHWTVKQFTEYETVGILVPAVAGSGGVLFIWSLRKCTNSAIL 392
            |.:.|    |:..|...| :|....|...|.......|..:...:..|.::|....|..|
Human   290 AIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAGYTIFITSFLGVLVFSRCFRDTT----- 349

  Fly   393 WLALVSLLSHCSSSLMKGFALESWQIYVAIGLGVFKSLVNPMCRTMITNLLPADERGKIFALLGV 457
             :.::.::|..|.:|:..|..|::..|:|..:.:|..:.....|:.::.|:.....||:|.:|.:
Human   350 -MIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQL 413

  Fly   458 LQALSPLISSTLYVAIYTRTLNTEPGIFNVFSAFLFGIGIILLGTVWHKK 507
            ..||:.:::||||..||..|::...|.....|:||..:.||.:..|.:|:
Human   414 SLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIVAYKQ 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8046	NP_724761.1	MFS_1	138..467	CDD:284993	80/360 (22%)
		MFS	141..503	CDD:119392	92/393 (23%)
SLC46A2	NP_149040.3	MFS_1	84..421	CDD:284993	81/361 (22%)
		MFS	<282..453	CDD:304372	43/177 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154043
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7720
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.800