DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8046 and SPAC14C4.07

DIOPT Version :9

Sequence 1:	NP_724761.1	Gene:	CG8046 / 35936	FlyBaseID:	FBgn0033388	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_594912.1	Gene:	SPAC14C4.07 / 2541546	PomBaseID:	SPAC14C4.07	Length:	644	Species:	Schizosaccharomyces pombe

Alignment Length:	549	Identity:	115/549 - (20%)
Similarity:	208/549 - (37%)	Gaps:	136/549 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 QASRPQSLGMYLLEPFILILLFAYNFSSTVLKNEVIYQSCTAGFGY-------PDSVCQLLGTKN 109
            :.:|.:||...|:.|...|..|::......|...:..:.|...:..       .|.:|:|   ..
pombe   119 EIARRRSLSPLLILPLNFINAFSWGMIEIPLLFLLRQELCAIHYNLDPTQLSPDDPICRL---AE 180

  Fly   110 ITNETKRIEEQVQPYAAQVTLAMRLVECFIPAFCGLFA----GSWADHYGRKPLLM--CSFLGYG 168
            ||....::.      ||..:||         ||.|||:    |:..|.|||:.:|.  .|||..|
pombe   181 ITTGVSKVR------AAFGSLA---------AFLGLFSTAYYGTMGDIYGRRLVLFITVSFLLLG 230

  Fly   169 LQYLISAAIAYCAMYTQGLVSPWWYVLSIVPLSCLGSSVTYSVAAV-CFIADVSGGKVRSYRMIA 232
            ..:|:..:.|....|         :||....|..||..::..||:. .|:||.|..:.|::.:..
pombe   231 DLWLLYQSYAPKHPY---------FVLFAAALKGLGGYISTVVASQNSFVADCSKTEFRAWYLGL 286

  Fly   233 YELAIYVGLLLGSLGSGYAYEAT-DAYIVFSISAVCIFTALFLMALLLPESLPARNRTLSTPTTD 296
            ...|.::|..||...||:..:.| ..|.||.|::......|..:.|:|||||     .:|.....
pombe   287 NFAAYHLGTALGPSLSGFIVQYTPHMYYVFYITSTFWIIYLLYVWLILPESL-----DVSESKEQ 346

  Fly   297 TSVVSMLKSLWSTCSKP-----------------------------REHQNRFMLTTIMVVLLLT 332
            .:.:|...|:|.:|.:|                             |.|.: .:|..|::.|.|
pombe   347 QNKISGFSSIWRSCLEPLIILWPRSLCTEESCEFHQYDINADTHAGRRHWD-VLLAAILISLTL- 409

  Fly   333 AFVSDGSNSVFYKFMRIKFHW---------TVKQFTEYETVGILVPAVA-----------GSGGV 377
              :..||..:...:...||.|         :...|....|:..|.|.::           .|.|:
pombe   410 --LGAGSMGLLPLYTDYKFGWGPMKASLILSTDSFASSITLVALFPLLSKVIEKIIEKLYSSEGL 472

  Fly   378 ------------------LFIWSLRK-CTNSAIL----------------WLALVSLLSHCSSSL 407
                              :|.:.:|. .:.|:||                |.|.:......|:::
pombe   473 FEDPSRADNTSSLQGIRNVFSYLVRPGYSRSSILRGRTADEKYTIVKRDVWNAQLGYAIALSAAV 537

  Fly   408 MKGFALESWQIYVAIGLGVFKSLVNPMCRTMITNLLPADERGKIFALLGVLQALSPLISSTLYVA 472
            :...|.....::.|:.:....::|.|..:::..|.:.::..|::.|...|.:|::.:|...:|..
pombe   538 LLAVAKSDVALFTAVIIQAISNMVVPCVQSIALNGVQSEYNGRVLAAFAVFEAVALIIRGPIYAF 602

  Fly   473 IYTRTLNTE-PGIFNVFSAFLFGIGIILL 500
            :||.::... |.:....||.::|...|::
pombe   603 VYTESMKVSYPNMIFFLSAVIYGCCFIII 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8046	NP_724761.1	MFS_1	138..467	CDD:284993	89/420 (21%)
CG8046	NP_724761.1	MFS	141..503	CDD:119392	97/453 (21%)
SPAC14C4.07	NP_594912.1	MFS	190..>335	CDD:119392	47/162 (29%)
SPAC14C4.07	NP_594912.1	MFS_1	194..459	CDD:284993	71/291 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_111049
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810