DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8046 and CG30345

DIOPT Version :9

Sequence 1:	NP_724761.1	Gene:	CG8046 / 35936	FlyBaseID:	FBgn0033388	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_724760.2	Gene:	CG30345 / 246553	FlyBaseID:	FBgn0050345	Length:	496	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	151/483 - (31%)
Similarity:	266/483 - (55%)	Gaps:	20/483 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 IAVGTEFPGNPQAS----RPQSLGMYLLEPFILILLFAYNFSSTVLKNEVIYQSCTAGFGYPDSV 101
            |.|.:..|.|...|    ||:||   :|||.:.::.|....:..|.:|:::||:|.....|..:.
  Fly    19 IEVRSPPPSNRTFSSWLKRPRSL---ILEPAVFLVFFGRFLTDAVYQNQILYQTCVTVMKYNATE 80

  Fly   102 CQ-LLGTKNITNETKRIEEQVQPYAAQVTLAMRLVECFIPAFCGLFAGSWADHYGRKPLLMCSFL 165
            |: .|||...::|.|:||.|||.||:.:|:...::|..:||...||.|.|:|.:||:|:|:.:|.
  Fly    81 CEPFLGTDRASDEVKKIEGQVQEYASTITMISSMLESTVPAIVSLFLGPWSDKFGRRPILLSTFT 145

  Fly   166 GYGLQYLISAAI--AYCAMYTQGLVSPWWYVLSIVPLSCLGSSVTYSVAAVCFIADVSGGKVRSY 228
            |    ||.||.|  ....:.|...:||||::||.||....|.:........|:::||:....|:.
  Fly   146 G----YLFSAIILVVLTQITTAVNISPWWFLLSSVPSVFSGGTCALITILYCYVSDVATENKRAM 206

  Fly   229 RMIAYELAIYVGLLLGSLGSGYAYEATDAYIVFSISAVCIFTALFLMALLLPESLPARNRTLSTP 293
            ||:..|.|:.:|::.|.:.|||.|.||.|.|:|.:....|..||..:...:.|||.:.:....:.
  Fly   207 RMVTMEAALGLGMMAGGVASGYIYAATGASILFILVGSIISIALLYVYFFVAESLKSEDLETGSR 271

  Fly   294 TTDTSVVSMLKSLWSTCSKPREHQNRFMLTTIMVVLLLTAFVSDGSNSVFYKFMRIKFHWTVKQF 358
            ..:...:.::|.|..||.:.||:.:|.::..:|:.|.|..|..:|.::|.|.|||.:|.:||:.:
  Fly   272 IREFFRLDLVKVLVKTCIRKRENYDRAIIWFVMMSLTLCVFAMEGESTVNYMFMRKQFDYTVQDY 336

  Fly   359 TEYETVGILVPAVAGSGGVLFIWSLRKCTNSAILWLALVSLLSHCSSSLMKGFALESWQIYVAIG 423
            :.:....:::..|   |..:.:..||:....:.:.:.|::.......|.::..|:...::|:|:.
  Fly   337 SVFNAARVVIQVV---GSTIAMILLRRLLGLSTIMMTLLAFACCVLESTVRATAVYGSEMYLALM 398

  Fly   424 LGVFKSLVNPMCRTMITNLLPADERGKIFALLGVLQALSPLISSTLYVAIYTRTLNTEPGIFNVF 488
            :|:.:.:::|||:.:::::.|:.|.||||:|...||::|||.::.||.|:|..|:|..|||||..
  Fly   399 VGMMRGVMSPMCKAILSHVTPSSELGKIFSLTTSLQSISPLGAAPLYTAVYQATVNFYPGIFNFI 463

  Fly   489 SAFLFGIGIILLGTVWH-KKS--RNLVY 513
            |..|:.:...:...|:. :||  .|.||
  Fly   464 SVGLYFLCFCMSAAVFGIQKSMGSNSVY 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8046	NP_724761.1	MFS_1	138..467	CDD:284993	98/330 (30%)
CG8046	NP_724761.1	MFS	141..503	CDD:119392	110/363 (30%)
CG30345	NP_724760.2	MFS_1	102..437	CDD:284993	100/341 (29%)
CG30345	NP_724760.2	MFS	121..472	CDD:119392	110/357 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458932
Domainoid	1	1.000	92	1.000	Domainoid score	I7560
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4421
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	1	1.000	-	-		FOG0001349
OrthoInspector	1	1.000	-	-		mtm6480
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
	10	9.900