DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8046 and slc46a1

DIOPT Version :9

Sequence 1:	NP_724761.1	Gene:	CG8046 / 35936	FlyBaseID:	FBgn0033388	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001120610.1	Gene:	slc46a1 / 100145771	XenbaseID:	XB-GENE-961470	Length:	462	Species:	Xenopus tropicalis

Alignment Length:	517	Identity:	113/517 - (21%)
Similarity:	217/517 - (41%)	Gaps:	115/517 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SGDADPEVASTASEKQRSSGASAIAVGTEFPGNPQASRPQSLGMYLLEPFILILLFAYNFSSTVL 82
            |.|..|||    .|:.||                :...|.|:   .:||.:.:.:||...... |
Frog     3 SPDDSPEV----RERPRS----------------RRCLPASV---TVEPVLFLSMFALALQGP-L 43

  Fly    83 KNEVIYQSCTAGFGYPDS---VCQLLGTKNITNETKRIEEQVQPYAAQVTLAMRLVECFIPAFCG 144
            ..:.::...:|..|:..:   .|.:.|:|:    |..::::|:...:..:|.:.|....:..|..
Frog    44 TTQYLWDRLSADIGFNGTRILDCTVNGSKS----TGALQQEVETLTSHWSLYINLGGFLVGLFSV 104

  Fly   145 LFAGSWADHYGRKPLLMCSFLGYGLQYLISAAIAYCAMYTQGLVSPWWYVLSIVPLSCLGSSVTY 209
            :..|.|:|..||:|:|....:|..||    ||:....||.:..|:   |.|  :.....|.|..:
Frog   105 MLLGPWSDKVGRRPVLFFPCIGLALQ----AALYLVVMYQELHVA---YFL--IGRFISGISGDF 160

  Fly   210 S-VAAVCF--IADVSGGKVRSYRMIAYELAIYVGLLLGSLGSGYAYEATDAYI--VFSISAVCIF 269
            : :.|.||  |||||..:.|::|:...|..:.:..::.|:..|: :.....||  .:.:.||.:|
Frog   161 NMILAGCFAYIADVSDRQSRTFRVAILEACLGIAGMVASIIGGH-WRKAQGYINPFWLVFAVNLF 224

  Fly   270 TALFLMALLLPESL----PARNRTLSTPTTDTSVVSMLKSLWSTCSKPREHQNRFMLTTI----- 325
            ||:::. ..:.||:    |||..|                       .|.:|..|.|.|:
Frog   225 TAVYVY-FCVEESVKDKKPARLFT-----------------------HRHYQTFFRLFTVSGENN 265

  Fly   326 --------MVVLLLTAFVSDGSNSVFYKF-MRIKFHWTVKQFTEYETVGILVPAVAGSGG--VLF 379
                    .:.||:...|..|:.::|..: :.....|      :.:.:|.      ||..  :.:
Frog   266 RRRKLCLYSLALLVVVTVHMGAKNLFVLYELSYPLCW------DSDLIGY------GSAAEHLTY 318

  Fly   380 IWSL------RKCTNSAILWLALVSLLSHCSSSLMKGFALESWQIYVAIGLGVFKSLVNPMCRTM 438
            :.||      :.|.  |..|:|.:..:|:.|..::...|..:..::...||..|.....|:.|:.
Frog   319 LSSLAGLRLFQLCL--ADSWVAEMGFISNISGLVVISLASTTPVMFTGYGLRFFAMATTPVIRSK 381

  Fly   439 ITNLLPADERGKIFALLGVLQALSPLISSTLYVAIYTRTLNTEPGIFNVFSAFLFGIGIILL 500
            ::.::...|:|.:|:.:..::.||.|:::.::.::|..||:...|.     .||||..::|:
Frog   382 LSKMVEEGEQGALFSSVACVEGLSYLLATAVFNSLYPATLHFMQGF-----PFLFGALLLLI 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8046	NP_724761.1	MFS_1	138..467	CDD:284993	80/359 (22%)
CG8046	NP_724761.1	MFS	141..503	CDD:119392	89/391 (23%)
slc46a1	NP_001120610.1	MFS	79..446	CDD:119392	92/413 (22%)
slc46a1	NP_001120610.1	MFS_1	97..410	CDD:284993	80/360 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I7096
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4704
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47543
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060