Protein Alignment CG8046 and slc46a1

DIOPT Version :10

• Sequence 1: NP_724761.1
• Gene: CG8046 / 35936
• FlyBaseID: FBgn0033388
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001120610.1
• Gene: slc46a1 / 100145771
• XenbaseID: XB-GENE-961470
• Length: 462
• Species: Xenopus tropicalis
• Alignment Length: 517
• Identity: 113/517 - (21%)
• Similarity: 217/517 - (41%)
• Gaps: 115/517 - (22%)

  Fly    18 SGDADPEVASTASEKQRSSGASAIAVGTEFPGNPQASRPQSLGMYLLEPFILILLFAYNFSSTVL 82
            |.|..|||    .|:.||                :...|.|:   .:||.:.:.:||...... |
 Frog     3 SPDDSPEV----RERPRS----------------RRCLPASV---TVEPVLFLSMFALALQGP-L 43

  Fly    83 KNEVIYQSCTAGFGYPDS---VCQLLGTKNITNETKRIEEQVQPYAAQVTLAMRLVECFIPAFCG 144
            ..:.::...:|..|:..:   .|.:.|:|:    |..::::|:...:..:|.:.|....:..|..
 Frog    44 TTQYLWDRLSADIGFNGTRILDCTVNGSKS----TGALQQEVETLTSHWSLYINLGGFLVGLFSV 104

  Fly   145 LFAGSWADHYGRKPLLMCSFLGYGLQYLISAAIAYCAMYTQGLVSPWWYVLSIVPLSCLGSSVTY 209
            :..|.|:|..||:|:|....:|..||    ||:....||.:..|:   |.|  :.....|.|..:
 Frog   105 MLLGPWSDKVGRRPVLFFPCIGLALQ----AALYLVVMYQELHVA---YFL--IGRFISGISGDF 160

  Fly   210 S-VAAVCF--IADVSGGKVRSYRMIAYELAIYVGLLLGSLGSGYAYEATDAYI--VFSISAVCIF 269
            : :.|.||  |||||..:.|::|:...|..:.:..::.|:..|: :.....||  .:.:.||.:|
 Frog   161 NMILAGCFAYIADVSDRQSRTFRVAILEACLGIAGMVASIIGGH-WRKAQGYINPFWLVFAVNLF 224

  Fly   270 TALFLMALLLPESL----PARNRTLSTPTTDTSVVSMLKSLWSTCSKPREHQNRFMLTTI----- 325
            ||:::. ..:.||:    |||..|                       .|.:|..|.|.|:
 Frog   225 TAVYVY-FCVEESVKDKKPARLFT-----------------------HRHYQTFFRLFTVSGENN 265

  Fly   326 --------MVVLLLTAFVSDGSNSVFYKF-MRIKFHWTVKQFTEYETVGILVPAVAGSGG--VLF 379
                    .:.||:...|..|:.::|..: :.....|      :.:.:|.      ||..  :.:
 Frog   266 RRRKLCLYSLALLVVVTVHMGAKNLFVLYELSYPLCW------DSDLIGY------GSAAEHLTY 318

  Fly   380 IWSL------RKCTNSAILWLALVSLLSHCSSSLMKGFALESWQIYVAIGLGVFKSLVNPMCRTM 438
            :.||      :.|.  |..|:|.:..:|:.|..::...|..:..::...||..|.....|:.|:.
 Frog   319 LSSLAGLRLFQLCL--ADSWVAEMGFISNISGLVVISLASTTPVMFTGYGLRFFAMATTPVIRSK 381

  Fly   439 ITNLLPADERGKIFALLGVLQALSPLISSTLYVAIYTRTLNTEPGIFNVFSAFLFGIGIILL 500
            ::.::...|:|.:|:.:..::.||.|:::.::.::|..||:...|.     .||||..::|:
 Frog   382 LSKMVEEGEQGALFSSVACVEGLSYLLATAVFNSLYPATLHFMQGF-----PFLFGALLLLI 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8046	NP_724761.1	MFS_SLC46	61..504	CDD:340944	103/474 (22%)
slc46a1	NP_001120610.1	MFS_SLC46A1_PCFT	23..447	CDD:341007	104/477 (22%)