Protein Alignment CG8008 and MFSD14B

DIOPT Version :9

• Sequence 1: NP_001137623.1
• Gene: CG8008 / 35935
• FlyBaseID: FBgn0033387
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_115947.2
• Gene: MFSD14B / 84641
• HGNCID: 23376
• Length: 506
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 92/492 - (18%)
• Similarity: 165/492 - (33%)
• Gaps: 179/492 - (36%)

  Fly    86 QPYVANLFLARTLLESIVPAFCGL---FIGSWSDHYGRKPLLIVSMIGFSASF---LMMAAICEL 144
            :.:..:.||...|::.:......|   .||:.||.:||||.|:.::  |...|   ||.
Human    72 ETFSQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTV--FFTCFPIPLMR------ 128

  Fly   145 SSYYVVNPWWYIMAAVPHSLLGGNCVFSV---AAFCFISDITDCKSRPYRMIFMESLFFIGLTSG 206
                 ::||||.      :::..:.||||   ..|.:::|:|....|.....::.:.|...|.|.
Human   129 -----ISPWWYF------AMISVSGVFSVTFSVIFAYVADVTQEHERSTAYGWVSATFAASLVSS 182

  Fly   207 SLLSSFVYAAVGSAATIGISGCIVTFATLFIIFFVPESLHFHKEQETKNAITANVEKECIDSKVP 271
            ..:.:::.|:.|.:..:.::..:......||:..|||||
Human   183 PAIGAYLSASYGDSLVVLVATVVALLDICFILVAVPESL-------------------------- 221

  Fly   272 ITACDLQLDRVAIDCPPNFMNDEEPGKDKRMELPTPATPAMSFDDDLLAKYVERLPQKAEERKRQ 336
                                    |.|.:    |......:|:                   |:.
Human   222 ------------------------PEKMR----PVSWGAQISW-------------------KQA 239

  Fly   337 EAEEQAKKAGLFSMVHIRDMISTCFKRRDHHARAIIWLVTLAMFLSIFVFDGVMTVMYLFVREKF 401
            :.....||.|..|.|                     .|:.:.:|||.....|..:..:|::|:..
Human   240 DPFASLKKVGKDSTV---------------------LLICITVFLSYLPEAGQYSSFFLYLRQVI 283

  Fly   402 HW-TVRDYTFFETVSHLVPMIGAL-----IGFL--ILRKVFRLSVVTLAL------LAFFSEILN 452
            .: :|:       ::..:.|:|.|     ..||  ::|.:...:.|.|.|      ||::
Human   284 GFGSVK-------IAAFIAMVGILSIVAQTAFLSILMRSLGNKNTVLLGLGFQMLQLAWY----- 336

  Fly   453 NLAKGFATMPWHMYLSVTLGVFRSISGPMCRTIVSNIVPPSDLGKIFSIKNVLQSFAPFVAAPLY 517
                ||.:..|.|:.:.|:....||:.|....:||........|       |.|..
Human   337 ----GFGSQAWMMWAAGTVAAMSSITFPAISALVSRNAESDQQG-------VAQGI--------- 381

  Fly   518 TLIYKRSLTTYPGLFNFVSSFLYLLSFVFIGYVLRIK 554
                   :|...||.|.:...||  .|:|  |:..::
Human   382 -------ITGIRGLCNGLGPALY--GFIF--YMFHVE 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8008	NP_001137623.1	MFS	101..547	CDD:119392	87/468 (19%)
		MFS_1	101..>261	CDD:284993	38/168 (23%)
		MFS_1	375..>558	CDD:284993	40/194 (21%)
MFSD14B	NP_115947.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		MFS	48..450	CDD:119392	92/492 (19%)
		MFS_1	49..394	CDD:284993	87/473 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	457..481

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D763423at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820