Protein Alignment CG8008 and MFSD14A

DIOPT Version :9

• Sequence 1: NP_001137623.1
• Gene: CG8008 / 35935
• FlyBaseID: FBgn0033387
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_149044.2
• Gene: MFSD14A / 64645
• HGNCID: 23363
• Length: 490
• Species: Homo sapiens
• Alignment Length: 478
• Identity: 88/478 - (18%)
• Similarity: 159/478 - (33%)
• Gaps: 147/478 - (30%)

  Fly    86 QPYVANLFLARTLLESIVPAFCGL---FIGSWSDHYGRKPLLIVSMIGFSASFLMMAAICELSSY 147
            :.:..:.||...|::.:......|   .||:.||.:|||..|::::....|...:|.
Human    64 ETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMK-------- 120

  Fly   148 YVVNPWWYIMAAVPHSLLGGNCVFSV---AAFCFISDITDCKSRPYRMIFMESLFFIGLTSGSLL 209
              ::||||.      :::..:.||:|   ..|.:::|||....|......:.:.|...|.:...:
Human   121 --ISPWWYF------AVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAI 177

  Fly   210 SSFVYAAVGSAATIGISGCIVTFATLFIIFFVPESLHFHKEQETKNAITANVEKECIDSKVPITA 274
            .:::....|.:..:.::..|......||:..|||||
Human   178 GAYLGRVYGDSLVVVLATAIALLDICFILVAVPESL----------------------------- 213

  Fly   275 CDLQLDRVAIDCPPNFMNDEEPGKDKRMELPTPATPAMSFDDDLLAKYVERLPQKAEERKRQEAE 339
                         |..|.....|.....|   .|.|..|.
Human   214 -------------PEKMRPASWGAPISWE---QADPFASL------------------------- 237

  Fly   340 EQAKKAGLFSMVHIRDMISTCFKRRDHHARAIIWLVTLAMFLSIFVFDGVMTVMYLFVREKFHWT 404
               ||.|..|                     |:.|:.:.:|||.....|..:..:|::|:...::
Human   238 ---KKVGQDS---------------------IVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFS 278

  Fly   405 VRDYTFFETVSHLVPMIG-ALIGFLILRKVFRLSVVTLALLAFFSEILNNLAKGFATMPWHMYLS 468
            ......|..|..::.:|. .::..|::|.:...:.:.|. |.|  :||.....||.:.||.|:.:
Human   279 PESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLG-LGF--QILQLAWYGFGSEPWMMWAA 340

  Fly   469 VTLGVFRSISGPMCRTIVSNIVPPSDLGKIFSIKNVLQSFAPFVAAPLYTLIYKRSLTTYPGLFN 533
            ..:....||:.|....:||........|       |:|..                :|...||.|
Human   341 GAVAAMSSITFPAVSALVSRTADADQQG-------VVQGM----------------ITGIRGLCN 382

  Fly   534 FVSSFLYLLSFVFIGYVLRIKYR 556
            .:...||  .|:|  |:..::.:
Human   383 GLGPALY--GFIF--YIFHVELK 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8008	NP_001137623.1	MFS	101..547	CDD:119392	83/452 (18%)
		MFS_1	101..>261	CDD:284993	34/165 (21%)
		MFS_1	375..>558	CDD:284993	38/183 (21%)
MFSD14A	NP_149044.2	MFS_MFSD14	37..449	CDD:340945	88/478 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	465..490

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810