DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8008 and mfsd10

DIOPT Version :9

Sequence 1:	NP_001137623.1	Gene:	CG8008 / 35935	FlyBaseID:	FBgn0033387	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001017667.1	Gene:	mfsd10 / 550360	ZFINID:	ZDB-GENE-050417-154	Length:	450	Species:	Danio rerio

Alignment Length:	563	Identity:	108/563 - (19%)
Similarity:	202/563 - (35%)	Gaps:	175/563 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VVFMLLFSHTLSGTIQRNQVIYQTCTVIFHYNESDCKQLDVKNASAEINAI------------ET 83
            |||:.|....|..|:    ::....:::.||:::.      .|....:.::            ||
Zfish    19 VVFLALLLDLLGFTL----ILPLLPSILDHYSQTG------DNVYQSLQSVVDWFRGAVGAPMET 73

  Fly    84 ELQPYVANLF--LARTLLESIVPAFCGLFIGSWSDHYGRKPLLIVSMIGFSASFLMMAAICELSS 146
            :   |.:.||  |..:|. |::........|:.||.|||||||:::.||..||:::.|    .|.
Zfish    74 K---YNSVLFGGLIGSLY-SLLQFLSSPITGALSDDYGRKPLLLLTTIGLMASYVLWA----FSH 130

  Fly   147 YYVVNPWWYIMAAVPHSLLGGNCVFSVAAFC--FISDITDCKSRPYRMIFMESLFFIGLTSGSLL 209
            .:.|    ::::.:    :||.|..:| :.|  .::|:...|:|...|..:...|.:|.|.|.|:
Zfish   131 SFTV----FLLSRI----VGGICKGNV-SLCTAIVADLPCPKARNKGMAMIGVAFSLGFTLGPLM 186

  Fly   210 SSFVYAAVGSAATI--GISGCIVTFA---TLFIIFFVPESLHFHKEQETKNAI-TANVEKECIDS 268
            .::....:..|...  |.:...|.|:   .|||.|.:||:|.       |.|. ::.::::..|.
Zfish   187 GAYFALRLKDAEVFYQGPAMLAVLFSLADLLFIFFMLPETLQ-------KGASESSGLQQQSGDL 244

  Fly   269 KVPITACDLQLDRVAIDCPPNFMNDEEPGKDKRMELPTPATPAMSFDDDLLAKYVERLPQKAEER 333
            ..|:...             ||                              ..|.|......|:
Zfish   245 LHPVALF-------------NF------------------------------TAVRRTENPPSEQ 266

  Fly   334 KRQEAEEQAKKAGLFSMVHIRDMISTCFKRRDHHARAIIWLVTLAMFLSIFVFDGVMTVMYLFVR 398
            |.|..:                                  ::.|..|..:|:|.|:...:.....
Zfish   267 KMQNLK----------------------------------VLGLVYFTYLFLFSGLEFTLSFLTH 297

  Fly   399 EKFHWT--VRDYTFFETVSHLVPMIGALIGFL------ILRKVFRLSVVTLALLAFFSEILNNLA 455
            ::|.::  .:...||        .||..:..:      .:|...::..|::|::......|
Zfish   298 QRFQFSSMQQGKMFF--------FIGITMAVIQGGYARRIRPGHQIQSVSMAIITLIPAFL---- 350

  Fly   456 KGFATMPWHMYLSVTLGVF-----RSISGPMCRTIVSNIVPPSDLGKIFSIKNVLQSFA----PF 511
              ...:.|::.|..: |:|     .:|..|...|.||.....|..|.:..|...|.:.|    |.
Zfish   351 --LVGIAWNLTLLYS-GLFLYSFAAAIVVPCLSTQVSGHGSASQKGTVMGILRSLGALARALGPI 412

  Fly   512 VAAPLYTLIYKRSLTTYPGLFNFVSSFLYLLSFVFIGYVLRIK 554
            ||:.:|.|....       |...:||..:::..:.:.   |:|
Zfish   413 VASSVYWLAGAE-------LCLIISSVFFIVPLILLS---RLK 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8008	NP_001137623.1	MFS	101..547	CDD:119392	90/470 (19%)
		MFS_1	101..>261	CDD:284993	45/167 (27%)
		MFS_1	375..>558	CDD:284993	38/197 (19%)
mfsd10	NP_001017667.1	MFS	71..445	CDD:119392	98/499 (20%)
mfsd10	NP_001017667.1	MFS_1	77..411	CDD:284993	86/446 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910