DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8008 and rtet

DIOPT Version :9

Sequence 1:	NP_001137623.1	Gene:	CG8008 / 35935	FlyBaseID:	FBgn0033387	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_524429.1	Gene:	rtet / 42500	FlyBaseID:	FBgn0028468	Length:	477	Species:	Drosophila melanogaster

Alignment Length:	558	Identity:	114/558 - (20%)
Similarity:	207/558 - (37%)	Gaps:	149/558 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SNAFTLEKLRNLQWEKVFRMFYIEPVVFMLLFSHTLSGTIQRNQVIYQTCTVIFHYNESDCKQLD 70
            :.|...|...|.:.||...|.||   :|:.|....|:.||    ::....:::.||.::|
  Fly    30 NKALDKEASENGKPEKSDPMIYI---IFVSLLFDLLAFTI----ILPLLPSLLEHYRQND----- 82

  Fly    71 VKNASAEINAIETELQPYVANLFLARTLLESIVPAFCGLFIGSW---------------SDHYGR 120
                |:.:.|:.|:...:...|..|.   :..:....|.|:||.               ||:|||
  Fly    83 ----SSGLYAVLTDRVRWFQQLLGAP---DRYISVLFGGFLGSMFSFLQFVASPIVGGLSDYYGR 140

  Fly   121 KPLLIVSMIGFSASFLMMAAICELSSYYVVNPWWYIMAAVPHSLLGGNCVFSVAAFCFISDITDC 185
            ||:|:....|.:.|:|:.|.    ||.:.:    :::|.....:..||....::.   |:|::..
  Fly   141 KPVLLACASGIALSYLIWAC----SSNFAL----FVLARFVGGISKGNISLCMSV---ITDVSSV 194

  Fly   186 KSRPYRMIFMESLFFIGLTSGSLLSS-FVYAAVGSAATIGISGCIVTFATLFIIFFVPESLHFHK 249
            |:|...|..:...|.:|...|.::.: |...:..|.:|               .|.:|..|.|..
  Fly   195 KTRGRGMALVGVAFSLGFIVGPMIGALFAIFSDKSGST---------------WFVLPSLLAFGL 244

  Fly   250 EQETKNAITANVEKECIDSKVPITACDLQLDRVAIDCPPNFMNDEEPGKDKRMELPTPATPAMSF 314
                  |:          ..:.:.||.|:               |...|:||::   ..:.|:|:
  Fly   245 ------AV----------GDLVVLACCLR---------------ETLPKEKRVK---EISSALSY 275

  Fly   315 DDDLLAKYVERLPQKAEERKRQEAEEQAKKAGLFSMVHIRDMISTCFKRRDHHARAIIWLVTLAM 379
            ...||                       ..:.:|....|:::     .::|..|...|.||   .
  Fly   276 GLQLL-----------------------NFSAIFRFAAIKNV-----PKKDIAALRSIGLV---Y 309

  Fly   380 FLSIFVFDGVMTVMYLFVREKFHWTVRDYT-FFETVSHLVPMI-GALIGFLILRKVFRLSVVTLA 442
            ||.:|::.|:...:...:..||.:|..|.. .|.|...::.:: |:::..|...|:...::.:|.
  Fly   310 FLYLFLYSGLEFTVTFLMYHKFGYTSMDQAKMFLTTGVIMTLLQGSVVRRLPEAKIKGYAIFSLY 374

  Fly   443 LL--AFFSEILNNLAKGFATMPWHMYLSVTLGVFRSISGPMC-RTIVSNIVPPSDLGKIFSIKNV 504
            |:  ||   ::..||:|...    :|..:||....:.....| .|:||........|.:..|...
  Fly   375 LIVPAF---VVVGLAEGSRM----LYAGMTLFAISTAFAVTCLTTLVSKYGNDDQKGSVLGIFRS 432

  Fly   505 LQSFA----PFVAAPLY-------TLIYKRSLTTYPGL 531
            |.:.|    |.|....:       |.|....|..||.:
  Fly   433 LGALARALGPVVGCIAFWCVGSRITYIAGGLLLIYPAM 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8008	NP_001137623.1	MFS	101..547	CDD:119392	93/463 (20%)
		MFS_1	101..>261	CDD:284993	37/175 (21%)
		MFS_1	375..>558	CDD:284993	39/173 (23%)
rtet	NP_524429.1	MFS	105..466	CDD:119392	91/458 (20%)
rtet	NP_524429.1	MFS_1	108..442	CDD:284993	86/431 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910