DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8008 and Vmat

DIOPT Version :9

Sequence 1:	NP_001137623.1	Gene:	CG8008 / 35935	FlyBaseID:	FBgn0033387	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001014525.1	Gene:	Vmat / 3346192	FlyBaseID:	FBgn0260964	Length:	646	Species:	Drosophila melanogaster

Alignment Length:	235	Identity:	49/235 - (20%)
Similarity:	86/235 - (36%)	Gaps:	44/235 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 NESDCKQLDVKNASAEINAIETELQPYVANLFLARTLLESIVPAFCGLFIGSWSDHYGRKPLLIV 126
            ||:..::|:.::.......:|..|      ||.::..::.:|....|             ||  .
  Fly   218 NETYYRELEERHNELVGETVEVGL------LFASKAFVQLLVNPIVG-------------PL--T 261

  Fly   127 SMIGFSASFLMMAAICELSSYYVVNPWWYIMAAVPHSLLG-GNCVFSVAAFCFISD-ITDCKSRP 189
            ..||:|........|..||:........|::..|..:|.| |:...||:....::| .||.|.|.
  Fly   262 HRIGYSIPMFAGFVIMFLSTIIFAFGRSYLVLFVARALQGIGSSCSSVSGMGMLADRFTDDKERG 326

  Fly   190 YRMIFMESLFFIGLTSGSLLSSFVYAAVGSAATIGISGCIVTFATLFIIFFVPESLHFHKEQETK 254
            ..|........:|:..|......:|..||.:|...|...:.....|..:|.:..|:   ::.||:
  Fly   327 NAMGIALGGLALGVLIGPPFGGVMYEFVGKSAPFLILAALALGDGLLQLFMLQPSI---QKAETE 388

  Fly   255 -----------------NAIT-ANVEKECIDSKVPITACD 276
                             .||| ||:....::..:|:...|
  Fly   389 PPSLKSLISDPYILIAAGAITFANMGIAMLEPSLPLWMVD 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8008	NP_001137623.1	MFS	101..547	CDD:119392	42/196 (21%)
		MFS_1	101..>261	CDD:284993	39/179 (22%)
		MFS_1	375..>558	CDD:284993
Vmat	NP_001014525.1	MFS	238..578	CDD:119392	46/215 (21%)
Vmat	NP_001014525.1	MFS_1	238..544	CDD:284993	46/215 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910