Protein Alignment CG8008 and SLC46A3

DIOPT Version :9

• Sequence 1: NP_001137623.1
• Gene: CG8008 / 35935
• FlyBaseID: FBgn0033387
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001129391.1
• Gene: SLC46A3 / 283537
• HGNCID: 27501
• Length: 463
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 109/548 - (19%)
• Similarity: 202/548 - (36%)
• Gaps: 150/548 - (27%)

  Fly    24 RMFYIEPVVFMLLFSHTLSGTIQRNQVIYQ-------TCTVIFHYNESDCKQLDVKNASAEINAI 81
            ::.::||.:|:..|:.||:|.: ..|.:|:       ..|.....|.|:|:    ||.|:.|.|.
Human     2 KILFVEPAIFLSAFAMTLTGPL-TTQYVYRRIWEETGNYTFSSDSNISECE----KNKSSPIFAF 61

  Fly    82 ETELQPYVANLFLARTLLESIVPAFCGLFI-GSWSDHYGRKPLLIVSMIGFSASFLMMAAICELS 145
            :.|:|..|:. |..:..:..::|.....|| .|.|||||||..:|:|.:|..|:.:.:..:|
Human    62 QEEVQKKVSR-FNLQMDISGLIPGLVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLC--- 122

  Fly   146 SYYVVNPWWYIMAAVPHSLLGGNC----VFSVAAFCFISDITDCKSRPYRMIFMESLFFI----- 201
              |...|:..::|:   :.:|..|    .|..|.|.:|.|  .||....:.|.:..:.|:
Human   123 --YFAFPFQLLIAS---TFIGAFCGNYTTFWGACFAYIVD--QCKEHKQKTIRIAIIDFLLGLVT 180

  Fly   202 ---GLTSGSLLS------SFVYAAVGSAATIGISGCIVTFATLFIIFFVPESLHFHKEQETKNAI 257
               ||:||..:.      ||:..||..|..:           ::|:||:.:
Human   181 GLTGLSSGYFIRELGFEWSFLIIAVSLAVNL-----------IYILFFLGD-------------- 220

  Fly   258 TANVEKECIDSKVPITACDLQLDRVAIDCPPNFMNDEEPGKDKRMELPTPATPAMSFDDDLLAKY 322
                         |:..|..|  .|.:.|...|.|
Human   221 -------------PVKECSSQ--NVTMSCSEGFKN------------------------------ 240

  Fly   323 VERLPQKAEERKRQEAEEQAKKAGLFSMVHIRDMISTCFKRRDHHARAIIWLVTLAMFLSIFVFD 387
                                    ||...::      .||......|.::.|:...:....||..
Human   241 ------------------------LFYRTYM------LFKNASGKRRFLLCLLLFTVITYFFVVI 275

  Fly   388 GVMTVMYLF-VREKFHWTVRDYTFFETVSHL--VPMIGALIGFLILRKVFRLSVVTLALLAFFSE 449
            |:..:..|: :.....|   :..|....|.|  ...:.:.:|..:..  :.:..:.:|.:..|:.
Human   276 GIAPIFILYELDSPLCW---NEVFIGYGSALGSASFLTSFLGIWLFS--YCMEDIHMAFIGIFTT 335

  Fly   450 ILNNLAKGFATMPWHMYLSVTLGVFRSISGPMCRTIVSNIVPPSDLGKIFSIKNVLQSFAPFVAA 514
            :.......||:....|:|:....:|..:...:.|:::|.:|..::.|.:|:....|::.....|.
Human   336 MTGMAMTAFASTTLMMFLARVPFLFTIVPFSVLRSMLSKVVRSTEQGTLFACIAFLETLGGVTAV 400

  Fly   515 PLYTLIYKRSLTTYPGLFNFVSSFLYLL 542
            ..:..||..::..|||....:|:.|.||
Human   401 STFNGIYSATVAWYPGFTFLLSAGLLLL 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8008	NP_001137623.1	MFS	101..547	CDD:119392	87/464 (19%)
		MFS_1	101..>261	CDD:284993	42/178 (24%)
		MFS_1	375..>558	CDD:284993	32/171 (19%)
SLC46A3	NP_001129391.1	MFS_1	81..399	CDD:311564	77/432 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6826
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4780
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8463
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.980