DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8008 and Mfsd14a

DIOPT Version :9

Sequence 1:NP_001137623.1 Gene:CG8008 / 35935 FlyBaseID:FBgn0033387 Length:566 Species:Drosophila melanogaster
Sequence 2:NP_032272.2 Gene:Mfsd14a / 15247 MGIID:1201609 Length:490 Species:Mus musculus


Alignment Length:478 Identity:88/478 - (18%)
Similarity:159/478 - (33%) Gaps:147/478 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    86 QPYVANLFLARTLLESIVPAFCGL---FIGSWSDHYGRKPLLIVSMIGFSASFLMMAAICELSSY 147
            :.:..:.||...|::.:......|   .||:.||.:|||..|::::....|...:|.        
Mouse    64 ETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMK-------- 120

  Fly   148 YVVNPWWYIMAAVPHSLLGGNCVFSV---AAFCFISDITDCKSRPYRMIFMESLFFIGLTSGSLL 209
              ::||||.      :::..:.||:|   ..|.:::|||....|......:.:.|...|.:...:
Mouse   121 --ISPWWYF------AVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAI 177

  Fly   210 SSFVYAAVGSAATIGISGCIVTFATLFIIFFVPESLHFHKEQETKNAITANVEKECIDSKVPITA 274
            .:::....|.:..:.::..|......||:..|||||                             
Mouse   178 GAYLGRVYGDSLVVVLATAIALLDICFILVAVPESL----------------------------- 213

  Fly   275 CDLQLDRVAIDCPPNFMNDEEPGKDKRMELPTPATPAMSFDDDLLAKYVERLPQKAEERKRQEAE 339
                         |..|.....|.....|   .|.|..|.                         
Mouse   214 -------------PEKMRPASWGAPISWE---QADPFASL------------------------- 237

  Fly   340 EQAKKAGLFSMVHIRDMISTCFKRRDHHARAIIWLVTLAMFLSIFVFDGVMTVMYLFVREKFHWT 404
               ||.|..|                     |:.|:.:.:|||.....|..:..:|::|:...::
Mouse   238 ---KKVGQDS---------------------IVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFS 278

  Fly   405 VRDYTFFETVSHLVPMIG-ALIGFLILRKVFRLSVVTLALLAFFSEILNNLAKGFATMPWHMYLS 468
            ......|..|..::.:|. .::..|::|.:...:.:.|. |.|  :||.....||.:.||.|:.:
Mouse   279 PESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLG-LGF--QILQLAWYGFGSEPWMMWAA 340

  Fly   469 VTLGVFRSISGPMCRTIVSNIVPPSDLGKIFSIKNVLQSFAPFVAAPLYTLIYKRSLTTYPGLFN 533
            ..:....||:.|....:||........|       |:|..                :|...||.|
Mouse   341 GAVAAMSSITFPAVSALVSRTADADQQG-------VVQGM----------------ITGIRGLCN 382

  Fly   534 FVSSFLYLLSFVFIGYVLRIKYR 556
            .:...||  .|:|  |:..::.:
Mouse   383 GLGPALY--GFIF--YIFHVELK 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8008NP_001137623.1 MFS 101..547 CDD:119392 83/452 (18%)
MFS_1 101..>261 CDD:284993 34/165 (21%)
MFS_1 375..>558 CDD:284993 38/183 (21%)
Mfsd14aNP_032272.2 MFS_MFSD14 37..449 CDD:340945 88/478 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 466..490
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2816
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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