Protein Alignment CG8008 and SLC46A1

DIOPT Version :9

• Sequence 1: NP_001137623.1
• Gene: CG8008 / 35935
• FlyBaseID: FBgn0033387
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_542400.2
• Gene: SLC46A1 / 113235
• HGNCID: 30521
• Length: 459
• Species: Homo sapiens
• Alignment Length: 524
• Identity: 101/524 - (19%)
• Similarity: 191/524 - (36%)
• Gaps: 129/524 - (24%)

  Fly    28 IEPVVFMLLFSHTLSGTIQRNQVIYQTCTVIFHYN----ESDCKQLDVKNASAEINAIETELQPY 88
            :||:||:..|:..|.|.: ..|.::...:....||    ...|..   ::|...:..:||....:
Human    25 VEPLVFLANFALVLQGPL-TTQYLWHRFSADLGYNGTRQRGGCSN---RSADPTMQEVETLTSHW 85

  Fly    89 VANLFLARTLLESIVPAFCGLF----IGSWSDHYGRKPLLIVSMIGFSASFLMMAAICELSSYYV 149
                    ||..::.....|||    :|:|||..||:|||:::.:|.....|:...:.:|.
Human    86 --------TLYMNVGGFLVGLFSSTLLGAWSDSVGRRPLLVLASLGLLLQALVSVFVVQLQ---- 138

  Fly   150 VNPWWYIMAAVPHSLLGGNCVFSVAAFCFISDITDCKSRPYRMIFMESLFFIGLTSGSLLSSFVY 214
            ::..::::..:..:|||.......|:|..::|::..:||.:||..:|:...:.....|||.....
Human   139 LHVGYFVLGRILCALLGDFGGLLAASFASVADVSSSRSRTFRMALLEASIGVAGMLASLLGGHWL 203

  Fly   215 AAVGSAATIGISGCIVTFATLFIIFFVPESLHFHKEQETKNAITANVEKECIDSKVPITACDLQL 279
            .|.|.|....::..::...||:..|...|:|
Human   204 RAQGYANPFWLALALLIAMTLYAAFCFGETL---------------------------------- 234

  Fly   280 DRVAIDCPPNFMNDEEPGKDKRMELPTPATPAMSFDDDLLAKYVERLPQKAEERKRQEAEEQAKK 344
                          :||                                              |.
Human   235 --------------KEP----------------------------------------------KS 239

  Fly   345 AGLFSMVHIRDMISTCFKRRDHHARAIIWLVTLAMFLSIFVFDGVMTVMYLF-VREKFHWTVRDY 408
            ..||:..|.|.::..........:|..:.|.:||:|:.|.|..|...::.|: :.....|..:..
Human   240 TRLFTFRHHRSIVQLYVAPAPEKSRKHLALYSLAIFVVITVHFGAQDILTLYELSTPLCWDSKLI 304

  Fly   409 TFFETVSHLVPMIGALIGFLILRKVFRLSVVTLALLAFFSEILNNLAKGFATMPWHMYLSVTLGV 473
            .:.....|| |.:.:|:...:|:  :.|:...:|.:.....||..:...|||:...|:....|..
Human   305 GYGSAAQHL-PYLTSLLALKLLQ--YCLADAWVAEIGLAFNILGMVVFAFATITPLMFTGYGLLF 366

  Fly   474 FRSISGPMCRTIVSNIVPPSDLGKIFSIKNVLQSFAPFVAAPLYTLIYKRSLTTYPGLFNFVSSF 538
            ...:..|:.|..:|.:|..::.|.:||....:.|.|...|:.::.       :.||...||:..|
Human   367 LSLVITPVIRAKLSKLVRETEQGALFSAVACVNSLAMLTASGIFN-------SLYPATLNFMKGF 424

  Fly   539 LYLL 542
            .:||
Human   425 PFLL 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8008	NP_001137623.1	MFS	101..547	CDD:119392	85/447 (19%)
		MFS_1	101..>261	CDD:284993	37/163 (23%)
		MFS_1	375..>558	CDD:284993	39/169 (23%)
SLC46A1	NP_542400.2	MFS	73..443	CDD:119392	89/472 (19%)
		MFS_1	94..407	CDD:284993	77/413 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6826
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	119	1.000	Inparanoid score	I4780
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48502
OrthoDB	1	1.010	-	-		D333052at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8463
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.980