Protein Alignment Prp38 and Prpf38a

DIOPT Version :10

• Sequence 1: NP_610463.2
• Gene: Prp38 / 35934
• FlyBaseID: FBgn0050342
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_766285.2
• Gene: Prpf38a / 230596
• MGIID: 1916962
• Length: 312
• Species: Mus musculus
• Alignment Length: 321
• Identity: 179/321 - (55%)
• Similarity: 225/321 - (70%)
• Gaps: 26/321 - (8%)

  Fly     1 MANRTVKEAKNVHGTNPQYLIEKIIRSRIYDSKYWKEQCFALTAELLVDKAMELRFVGGVYGGNI 65
            |||||||:|.::||||||||:|||||:|||:||||||:||.|||||:|||||||:||||||||||
Mouse     1 MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELKFVGGVYGGNI 65

  Fly    66 KPTQFLCLTLKMLQIQPEKDIVVEFIKNEEFKYVRALGAFYLRLTGAALDCYKYLEPLYIDNRKL 130
            |||.|||||||||||||||||:|||||||:|||||.|||.|:||||.|:||||||||||.|.||:
Mouse    66 KPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKI 130

  Fly   131 RRQNRAGQFEIVYMDEYIDELLRNDRVCDIILPRIQKRSILEENNEIEPKVSVLDEDLDDELPSD 195
            :.|||.|:|.::::||:|.|||.::|||||||||:|||.:|||..::||:||.|:||:||...|:
Mouse   131 KSQNRNGEFVLMHVDEFIYELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEEDMDDVESSE 195

  Fly   196 EEKADETNRPKENSTAVRR--------PRRV------RSKSRS---RSRERERRSGQGNSARSRD 243
            ||:.::....:..|...||        |||.      ||:|||   |||..:|||......|.|
Mouse   196 EEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPALRYRRSRSRSPRRRSRSPKRRSPSPRRERHR- 259

  Fly   244 YYDELEDYDRQRNRVRNRDTHNEDYDRRQNNGRHDRERERQDRDSIRERERDGDRDRRDRE 304
                  ....:|:|.|:||..:.  .|.::.|.|...|.|....|....::...:.||..|
Mouse   260 ------SKSPRRHRSRSRDRRHR--SRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp38	NP_610463.2	PRP38	10..172	CDD:460901	123/161 (76%)
		PRK12678	<193..>330	CDD:237171	36/129 (28%)
Prpf38a	NP_766285.2	N-terminal protein interaction domain. /evidence=ECO:0000250|UniProtKB:Q8NAV1	1..179		134/177 (76%)
		PRP38	10..172	CDD:460901	123/161 (76%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..312		42/139 (30%)