DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shrb and chmp4c

DIOPT Version :9

Sequence 1:	NP_610462.3	Gene:	shrb / 35933	FlyBaseID:	FBgn0086656	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_001017844.1	Gene:	chmp4c / 550542	ZFINID:	ZDB-GENE-050417-389	Length:	239	Species:	Danio rerio

Alignment Length:	211	Identity:	116/211 - (54%)
Similarity:	150/211 - (71%)	Gaps:	9/211 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PTTGEAIQKLRETENMLIKKQEFLEAKIEDELNIARKNASKNKRVALQALKKKKRLEKQLQQIDG 80
            |:..|||.:|||||.||.||||:||::||.|:.||:||.:||||.||||||:|||.|:||.||||
Zfish    38 PSPQEAINRLRETEAMLTKKQEYLESRIEQEIVIAKKNGTKNKRAALQALKRKKRFEQQLTQIDG 102

  Fly    81 TLSTIEMQREALESANTNTAVLTTMKNAADALKRAHQNMDVDKVHDMMDDIAEQQDVAREISDAI 145
            ||||||.|||:||:|.|||.||..|..||.|:|..|:.:|:||:..:|.||.|||:||:||||||
Zfish   103 TLSTIEFQRESLENATTNTEVLKNMGYAAKAIKGVHEKIDLDKIDSLMQDITEQQEVAQEISDAI 167

  Fly   146 SNPVAFGADLDDEDLERELDELEQENFDKEIIGIPEPTPTLPEAPTEDLPEKAKEKKKATTTTAV 210
            |.|  ||...|:::|..||.|||||:.::.:    :....||.|||..|| ..:...:||:...|
Zfish   168 SKP--FGDQFDEDELLAELAELEQEDLEESM----KSMGRLPSAPTHKLP-STRPSHRATSKKRV 225

  Fly   211 EDDDDPDMKQLLSWSN 226
            |||.  |||:|.||::
Zfish   226 EDDH--DMKRLASWAS 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shrb	NP_610462.3	Snf7	20..193	CDD:281366	101/172 (59%)
chmp4c	NP_001017844.1	Snf7	42..>173	CDD:281366	86/132 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	220	1.000	Domainoid score	I2553
eggNOG	1	0.900	-	-		E1_KOG1656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3193
OMA	1	1.010	-	-		QHG53573
OrthoDB	1	1.010	-	-		D1490465at2759
OrthoFinder	1	1.000	-	-		FOG0001179
OrthoInspector	1	1.000	-	-		otm25007
orthoMCL	1	0.900	-	-		OOG6_100985
Panther	1	1.100	-	-	O	PTHR22761
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1162
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.840