DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shrb and chmp4b

DIOPT Version :9

Sequence 1:	NP_610462.3	Gene:	shrb / 35933	FlyBaseID:	FBgn0086656	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_001004866.1	Gene:	chmp4b / 448169	XenbaseID:	XB-GENE-941865	Length:	222	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	133/229 - (58%)
Similarity:	165/229 - (72%)	Gaps:	13/229 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSFFGKMF--GGKKEVAPTTGEAIQKLRETENMLIKKQEFLEAKIEDELNIARKNASKNKRVALQ 63
            ||..||:|  |||....|:..|||||||:||.||.|||||||.|||.||..|:|:.:||||.|||
Frog     1 MSLIGKLFGTGGKGAKGPSPQEAIQKLRDTEEMLTKKQEFLEKKIEQELVTAKKHGTKNKRAALQ 65

  Fly    64 ALKKKKRLEKQLQQIDGTLSTIEMQREALESANTNTAVLTTMKNAADALKRAHQNMDVDKVHDMM 128
            |||:|||.||||.||||||||||.||||||:|||||.||..|..||.|:|.||.|||::||.::|
Frog    66 ALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKAAHDNMDIEKVDELM 130

  Fly   129 DDIAEQQDVAREISDAISNPVAFGADLDDEDLERELDELEQENFDKEIIGI--PEPTPTLPEAPT 191
            .|||:||::|:|||||||.||.||.|.|:::|..||:|||||..||.::.:  ||..| ||..|.
Frog   131 QDIADQQELAQEISDAISKPVGFGEDFDEDELMAELEELEQEELDKNLLEVQGPETVP-LPNVPA 194

  Fly   192 EDLPEKAKEKKKATTTTAVEDDDDPDMKQLLSWS 225
            ..||.|..:||        :::||.||::|.:|:
Frog   195 AVLPAKPVKKK--------QEEDDDDMRELENWA 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shrb	NP_610462.3	Snf7	20..193	CDD:281366	113/174 (65%)
chmp4b	NP_001004866.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		9/19 (47%)
		Snf7	22..158	CDD:367460	96/135 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	183..222		17/47 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	215	1.000	Domainoid score	I2662
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57102
Inparanoid	1	1.050	245	1.000	Inparanoid score	I3206
OMA	1	1.010	-	-		QHG53573
OrthoDB	1	1.010	-	-		D1490465at2759
OrthoFinder	1	1.000	-	-		FOG0001179
OrthoInspector	1	1.000	-	-		otm49459
Panther	1	1.100	-	-	LDO	PTHR22761
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1365
SonicParanoid	1	1.000	-	-		X1162
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110