DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shrb and chmp4bb

DIOPT Version :9

Sequence 1:	NP_610462.3	Gene:	shrb / 35933	FlyBaseID:	FBgn0086656	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_998622.1	Gene:	chmp4bb / 406766	ZFINID:	ZDB-GENE-040426-2812	Length:	224	Species:	Danio rerio

Alignment Length:	231	Identity:	136/231 - (58%)
Similarity:	171/231 - (74%)	Gaps:	14/231 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSFFGKMF--GGKKEVAPTTGEAIQKLRETENMLIKKQEFLEAKIEDELNIARKNASKNKRVALQ 63
            ||.|||:|  |||....||..||||||||||.||.:||:|||.||:.||.||:||.:||||.|||
Zfish     1 MSVFGKLFGGGGKGGKGPTPQEAIQKLRETEEMLAEKQDFLEKKIDAELLIAKKNGTKNKRAALQ 65

  Fly    64 ALKKKKRLEKQLQQIDGTLSTIEMQREALESANTNTAVLTTMKNAADALKRAHQNMDVDKVHDMM 128
            |||:|||.||||.||||||||||.||||||:|||||.||..|..||.|:|.||:|||:|||.|:|
Zfish    66 ALKRKKRYEKQLAQIDGTLSTIEFQREALENANTNTEVLKNMGFAAKAMKTAHENMDIDKVDDLM 130

  Fly   129 DDIAEQQDVAREISDAISNPVAFGADLDDEDLERELDELEQENFDKEIIGI--PEPTPTLPEAPT 191
            .||.|||::|:|||||||.||.||.:.|:::|..||:|||||..||:::.|  ||..| ||..|:
Zfish   131 QDITEQQELAQEISDAISRPVGFGEEFDEDELMAELEELEQEELDKDLLQISGPEDVP-LPNVPS 194

  Fly   192 EDLPEK--AKEKKKATTTTAVEDDDDPDMKQLLSWS 225
            ..||:|  ..:||:       :::|:.||::|.:|:
Zfish   195 NPLPKKTAVAQKKR-------QEEDEDDMEELKAWA 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shrb	NP_610462.3	Snf7	20..193	CDD:281366	115/174 (66%)
chmp4bb	NP_998622.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21		11/19 (58%)
		Snf7	22..158	CDD:281366	97/135 (72%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..224		16/50 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581231
Domainoid	1	1.000	220	1.000	Domainoid score	I2553
eggNOG	1	0.900	-	-		E1_KOG1656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3193
OMA	1	1.010	-	-		QHG53573
OrthoDB	1	1.010	-	-		D1490465at2759
OrthoFinder	1	1.000	-	-		FOG0001179
OrthoInspector	1	1.000	-	-		otm25007
orthoMCL	1	0.900	-	-		OOG6_100985
Panther	1	1.100	-	-	LDO	PTHR22761
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1365
SonicParanoid	1	1.000	-	-		X1162
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.890