DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shrb and chmp4ba

DIOPT Version :9

Sequence 1:	NP_610462.3	Gene:	shrb / 35933	FlyBaseID:	FBgn0086656	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_956489.1	Gene:	chmp4ba / 393164	ZFINID:	ZDB-GENE-040426-906	Length:	220	Species:	Danio rerio

Alignment Length:	229	Identity:	133/229 - (58%)
Similarity:	164/229 - (71%)	Gaps:	15/229 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSFFGKMFG----GKKEVAPTTGEAIQKLRETENMLIKKQEFLEAKIEDELNIARKNASKNKRVA 61
            ||.||||||    |.|..:|.  ||||:|||||.||.|||||||.|||.||..|:||.:||||.|
Zfish     1 MSLFGKMFGSGGKGGKSASPQ--EAIQRLRETEEMLTKKQEFLEKKIEQELVTAKKNGTKNKRAA 63

  Fly    62 LQALKKKKRLEKQLQQIDGTLSTIEMQREALESANTNTAVLTTMKNAADALKRAHQNMDVDKVHD 126
            |||||:|||.||||.||||||||||.||||||:|:|||.|:..|..||.|:|.||.|||:|||.:
Zfish    64 LQALKRKKRYEKQLAQIDGTLSTIEFQREALENAHTNTEVIKNMGYAAKAMKAAHDNMDIDKVDE 128

  Fly   127 MMDDIAEQQDVAREISDAISNPVAFGADLDDEDLERELDELEQENFDKEIIGIPEPTPTLPEAPT 191
            :|.||.|||::|:|||||||.||.||.:.|:::|..||:|||||..||.::.|.:..| ||..|:
Zfish   129 LMQDIIEQQELAQEISDAISKPVGFGEEFDEDELLAELEELEQEELDKNLLEIGDNVP-LPNVPS 192

  Fly   192 EDLPEKAKEKKKATTTTAVEDDDDPDMKQLLSWS 225
            ..||.:..:||        |::|:.|||.|.:|:
Zfish   193 TSLPSRPAKKK--------EEEDEDDMKDLEAWA 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shrb	NP_610462.3	Snf7	20..193	CDD:281366	111/172 (65%)
chmp4ba	NP_956489.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22		11/22 (50%)
		Snf7	22..157	CDD:281366	95/134 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	180..220		16/48 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581232
Domainoid	1	1.000	220	1.000	Domainoid score	I2553
eggNOG	1	0.900	-	-		E1_KOG1656
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H57102
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3193
OMA	1	1.010	-	-		QHG53573
OrthoDB	1	1.010	-	-		D1490465at2759
OrthoFinder	1	1.000	-	-		FOG0001179
OrthoInspector	1	1.000	-	-		otm25007
orthoMCL	1	0.900	-	-		OOG6_100985
Panther	1	1.100	-	-	O	PTHR22761
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1162
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770