DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shrb and vps-32.1

DIOPT Version :9

Sequence 1:	NP_610462.3	Gene:	shrb / 35933	FlyBaseID:	FBgn0086656	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_001370608.1	Gene:	vps-32.1 / 174091	WormBaseID:	WBGene00016961	Length:	221	Species:	Caenorhabditis elegans

Alignment Length:	227	Identity:	126/227 - (55%)
Similarity:	158/227 - (69%)	Gaps:	8/227 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSFFGKMFGGKKEVAPTT-GEAIQKLRETENMLIKKQEFLEAKIEDELNIARKNASKNKRVALQA 64
            ||.|||:|||:|:.||:| .|:||||||||.||.|||||||.|:.||...|.|..:||||:|||.
Worm     1 MSLFGKIFGGRKQEAPSTPQESIQKLRETEEMLEKKQEFLEKKVIDEKQNAVKYGTKNKRMALQC 65

  Fly    65 LKKKKRLEKQLQQIDGTLSTIEMQREALESANTNTAVLTTMKNAADALKRAHQNMDVDKVHDMMD 129
            |.:|:..||||..|||.||||..||||||:|:||..||..|..|:.|||.||.|||:|:|||:|:
Worm    66 LNRKRNFEKQLAHIDGVLSTIGYQREALENASTNAEVLNVMGTASKALKAAHNNMDIDQVHDLME 130

  Fly   130 DIAEQQDVAREISDAISNPVAFGADLDDEDLERELDELEQENFDKEIIGIPEPTPTLPEAPTEDL 194
            ||||||:||.||::||||||.|...:||:||.|||:.||||..|||::....|..|||:.|...|
Worm   131 DIAEQQEVANEIAEAISNPVGFSTAVDDDDLMRELEALEQEELDKELLDARAPPVTLPDTPNIAL 195

  Fly   195 PEKAKEKKKATTTTAVEDDDDPDMKQLLSWSN 226
            |.....:.:|       .:.|.|::.|.||:|
Worm   196 PAVPASRPRA-------KEADKDLEDLESWAN 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shrb	NP_610462.3	Snf7	20..193	CDD:281366	105/172 (61%)
vps-32.1	NP_001370608.1	Snf7	21..194	CDD:397437	105/172 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159513
Domainoid	1	1.000	204	1.000	Domainoid score	I1724
eggNOG	1	0.900	-	-		E1_KOG1656
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I2148
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53573
OrthoDB	1	1.010	-	-		D1490465at2759
OrthoFinder	1	1.000	-	-		FOG0001179
OrthoInspector	1	1.000	-	-		oto19875
orthoMCL	1	0.900	-	-		OOG6_100985
Panther	1	1.100	-	-	LDO	PTHR22761
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1365
SonicParanoid	1	1.000	-	-		X1162
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.840