Protein Alignment Hydr1 and Abhd3

DIOPT Version :9

• Sequence 1: NP_001188892.1
• Gene: Hydr1 / 35930
• FlyBaseID: FBgn0033382
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_598891.1
• Gene: Abhd3 / 106861
• MGIID: 2147183
• Length: 411
• Species: Mus musculus
• Alignment Length: 405
• Identity: 162/405 - (40%)
• Similarity: 233/405 - (57%)
• Gaps: 27/405 - (6%)

  Fly    95 YLSNLPRLHVLGMAV---------VAYVVYYLIQVVKRPIIACSDGPFKQYLIRKVPTLENKYWP 150
            ||.:..|:...|..|         |||..|||..:.|:|.:......|.::|....|.:...|:|
Mouse    18 YLEHQVRVGFFGSGVGLSLILGFSVAYACYYLSSIAKKPQLVIGGESFSRFLQDHCPVVTETYYP 82

  Fly   151 TFWCVESRAQTVLASLLRSKSLPRVNYRREILSLKDGGEVALDWMEEG-----CDQSA-PCILIL 209
            |.||.|||.||:|...:.||  |.|.||.|::...|||:::|||.:..     .|.|. |.||:|
Mouse    83 TVWCWESRGQTLLRPFITSK--PPVQYRNELIKTADGGQISLDWFDNNNSAYYVDASTRPTILLL 145

  Fly   210 PGLTGESQAEYIKCLVFAAQQAGMRVVVFNNRGLGGIELKTPRLYCAANCEDLCEVVQHVRRTLP 274
            |||||.|:..||..::..:::.|.|.|||||||:.|..|.|||.||.||.|||..||.||....|
Mouse   146 PGLTGTSKESYILHMIHLSEELGYRCVVFNNRGVAGESLLTPRTYCCANTEDLEAVVHHVHSLYP 210

  Fly   275 EKCKLGATGISMGGLILGNYLARKSDEARSFLSAAKIISVPWDVHKGSASIEKPVINSLLGRHLA 339
            ....| |.|:||||::|.|||.:..  :::.|.||...||.|:....|.|:|:|:...|...:|.
Mouse   211 GAPFL-AAGVSMGGMLLLNYLGKIG--SKTPLMAAATFSVGWNTFACSESLERPLNWLLFNYYLT 272

  Fly   340 GSLCRTLRNHLDIYRDIYQDSDIDIQRILRCKTIKEFDALFTAKQFGYAHVNDYYSDATLHNKLD 404
            ..|..:::.|..::.:     .||:.::::.|:|:|||..|||..|||..::|||:||:.:.:|.
Mouse   273 TCLQSSVKKHRHMFVE-----QIDMDQVMKAKSIREFDKRFTAVMFGYRTLDDYYTDASPNRRLK 332

  Fly   405 HISVPLLCLSAADDPFQPLDAIPIKAANQCTHVAIVITARGGHIGFLEGWWPSTKDQYMGRLFTE 469
            .:.:|:|||:|.||.|.|..||||:.|.|..:||:|:||.|||||||||.|| .:..||.|:|.:
Mouse   333 SVGIPVLCLNATDDVFSPSHAIPIETAKQNPNVALVLTAYGGHIGFLEGIWP-RQCTYMDRVFKQ 396

  Fly   470 YFTKALFDEDGEFQH 484
             |.:|:.:...|..:
Mouse   397 -FVQAMVEHGHELSN 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hydr1	NP_001188892.1	Abhydrolase	140..455	CDD:304388	138/320 (43%)
		Abhydrolase_1	206..453	CDD:278959	108/246 (44%)
Abhd3	NP_598891.1	PLN02511	39..403	CDD:215282	156/375 (42%)
		Abhydrolase	92..398	CDD:304388	135/317 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838153
Domainoid	1	1.000	198	1.000	Domainoid score	I3080
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14055
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2864
Isobase	1	0.950	-	0	Normalized mean entropy	S2599
OMA	1	1.010	-	-		QHG53891
OrthoDB	1	1.010	-	-		D1162019at2759
OrthoFinder	1	1.000	-	-		FOG0001372
OrthoInspector	1	1.000	-	-		otm43822
orthoMCL	1	0.900	-	-		OOG6_100540
Panther	1	1.100	-	-	O	PTHR10794
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2183
SonicParanoid	1	1.000	-	-		X867
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.890