Protein Alignment CG18659 and Denn2b

DIOPT Version :9

• Sequence 1: NP_665880.2
• Gene: CG18659 / 35929
• FlyBaseID: FBgn0027561
• Length: 908
• Species: Drosophila melanogaster
• Sequence 2: XP_011240242.1
• Gene: Denn2b / 76954
• MGIID: 108517
• Length: 1159
• Species: Mus musculus
• Alignment Length: 478
• Identity: 121/478 - (25%)
• Similarity: 195/478 - (40%)
• Gaps: 85/478 - (17%)

  Fly    10 KKLFEFWCEVTPTPGLERGTSSRSGGPAVPAGVIVESFPEGFRD-------QEVLTGIPSFAFP- 66
            ::|||::..|:    |::..|..:..|.|.     ..||:..|.       :|.|..||.|.||
Mouse   691 RELFEYFVVVS----LKKKPSRNTYLPEVS-----YQFPKLDRPTKQMREAEERLKAIPQFCFPD 746

  Fly    67 ----CDTTSTSVQTYSFVHTTGDSKWRFGFCR-------------------------------QD 96
                ...:..|.:|:||:.|..|...|||:||                               :.
Mouse   747 AKDWLPVSEYSSETFSFMLTGEDGSRRFGYCRRLLHTSTLCLCSFPSFLSENSMFGGRKEPSGKG 811

  Fly    97 PRTNTAMVLITYLPWHDTFLKLLPVLAELRRTDPNGFRTFLSEAYNQGIPDCGGSLKV---YYSA 158
            ||......:|:.|.....|.|:|..:...|.........|:........|..|.::||   ...|
Mouse   812 PRLPEVYCVISRLGCFGLFSKVLDEVERRRGISAALVYPFMRSLMESPFPAPGKTIKVKTFLPGA 876

  Fly   159 GQSHFTFERPLQFQLPSMPENHNLNLYYNFVEPKEMIAVFAAMLAERRIIFTSRHLDRLSSCIQA 223
            |.......||:..:|    |:.:....:..:..:::|.:||::|.|||:||.:..|..||||..|
Mouse   877 GNEVLELRRPMDSRL----EHVDFECLFTCLSVRQLIRIFASLLLERRVIFVADKLSTLSSCSHA 937

  Fly   224 ANAFLYPMVWQHIFIPVLPWEFKDYLGAPMPYLIGVPEPVLETVTSDELGEVVILNCDTKIFESP 288
            ..|.|||..|||.||||||....|.:..|.|:|:|:....|..:....:.|.:::|..:..|...
Mouse   938 VVALLYPFSWQHTFIPVLPASMIDIVCCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQ 1002

  Fly   289 FDDVHN-LPTEIVSQLKKHLNHTHDHIGD---------------RISKIFLNALVQLIGGYRDAV 337
            .||... ||.::.:.|::.|....:.|..               .:|::|:...|:.:|.|...:
Mouse  1003 MDDEDTLLPRKLQAALEQALERKSELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFL 1067

  Fly   338 EYHE-NSKTFNSQKFIES-RPAHLRPFLAKMMDLQIFAQFIDDRLTMLNSGLGFSDEFELETVRY 400
            .:.| ..:.|..:.|.:| ....:|.||...|:.|:||.||.||........|.   ||....:|
Mouse  1068 THSEKGERAFQREAFRKSVASKSIRRFLEVFMESQMFAGFIQDRELRKCRAKGL---FEQRVEQY 1129

  Fly   401 AEK----KKRGRNYAIMKNLKDK 419
            .|:    ::.|.| ..::.|.:|
Mouse  1130 LEELPDTEQSGMN-KFLRGLGNK 1151

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18659	NP_665880.2	uDENN	10..95	CDD:214824	29/127 (23%)
		DENN	98..282	CDD:280329	54/186 (29%)
		dDENN	315..379	CDD:129037	18/80 (23%)
Denn2b	XP_011240242.1	uDENN	694..781	CDD:214824	28/95 (29%)
		DENN	813..994	CDD:396629	53/184 (29%)
		dDENN	1045..1111	CDD:129037	18/65 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810