Protein Alignment CG18659 and Dennd2d

DIOPT Version :9

• Sequence 1: NP_665880.2
• Gene: CG18659 / 35929
• FlyBaseID: FBgn0027561
• Length: 908
• Species: Drosophila melanogaster
• Sequence 2: NP_082386.2
• Gene: Dennd2d / 72121
• MGIID: 2181193
• Length: 476
• Species: Mus musculus
• Alignment Length: 468
• Identity: 114/468 - (24%)
• Similarity: 196/468 - (41%)
• Gaps: 101/468 - (21%)

  Fly    23 PGLERGTSSRSGGPAVP-------------AG------------------------VIVESFPE- 49
            |.|..|.|..:.|.||.             ||                        .|...||:
Mouse    25 PRLRAGQSQNNPGEAVTEPERIQEHSPSSFAGGQHFFEYLLVVSLKKKRLGDDYEPTITYQFPKR 89

  Fly    50 -----GFRDQE--VLTGIPSFAFP-----CDTTSTSVQTYSFVHTTGDSKWRFGFCRQ------D 96
                 |.:::|  :|:.||.|.||     ...|....:|:|||.|..|...:.|:||:      .
Mouse    90 ENLLRGQQEEEDRLLSAIPLFCFPDGNEWAPLTEYPRETFSFVLTNVDGSRKIGYCRRLLPAGPG 154

  Fly    97 PRTNTAMVLITYLPWHDTFLKLL---------------PVLAELRRTD-PNGFRTFLSEAYNQGI 145
            |:......:|:.:.....|.|:|               |.:..||... |...:|...:::   |
Mouse   155 PQLPKVYCIISCIGCFGLFSKILDEVEKRHQISMAVIYPFMQGLREAAFPAPGKTVTLKSF---I 216

  Fly   146 PDCGGSLKVYYSAGQSHFTFERPLQFQLPSMPENHNLNLYYNFVEPKEMIAVFAAMLAERRIIFT 210
            ||          :|....:..|||...|    |:.:.::..:.:..:::|.:||:.:.||:|||.
Mouse   217 PD----------SGTEFISLTRPLDSHL----EHVDFSVLLHCLHLEQIIQIFASAVLERKIIFL 267

  Fly   211 SRHLDRLSSCIQAANAFLYPMVWQHIFIPVLPWEFKDYLGAPMPYLIGVPEPVLETVTSDELGEV 275
            :..|..||.||.||.|.|||..|.|.:|||:|......:..|.|:::||....|:.|....:.||
Mouse   268 AEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRFLQEVMDSPMEEV 332

  Fly   276 VILN-CDTKIFESPFDDVHNLP----TEIVSQLKKHLNH--THDHIGDRISKIFLNALVQLIGGY 333
            :::| |:.....|..|:...||    .:|:..|.:.:|.  |.:.|.:.:|..|:...|:.:|.|
Mouse   333 LLVNLCEGTFLLSVGDEKDILPPKLQDDILDSLGQGINELKTSEQINEHVSGPFVQFFVKTVGHY 397

  Fly   334 RDAVEYHENSK-TFNSQKFIESRPAHL-RPFLAKMMDLQIFAQFIDDRLTMLNSGLGFSDEFELE 396
            ...::...:.: .|..:.|.::..:.. |.|:.|.:..|:|:.||.:.....|...|:   |:.:
Mouse   398 ASYIKREASGQGHFQERSFCKAVTSKTKRRFVKKFVKTQLFSLFIQEAEKSRNPPAGY---FQKK 459

  Fly   397 TVRYAEKKKRGRN 409
            .:.|.|:||:.::
Mouse   460 ILEYEEQKKQKKS 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18659	NP_665880.2	uDENN	10..95	CDD:214824	29/121 (24%)
		DENN	98..282	CDD:280329	53/200 (27%)
		dDENN	315..379	CDD:129037	14/65 (22%)
Dennd2d	NP_082386.2	uDENN	57..149	CDD:214824	21/91 (23%)
		DENN	157..340	CDD:280329	53/199 (27%)
		dDENN	379..444	CDD:129037	14/64 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810