Protein Alignment CG18659 and dennd2db

DIOPT Version :10

• Sequence 1: NP_665880.2
• Gene: CG18659 / 35929
• FlyBaseID: FBgn0027561
• Length: 908
• Species: Drosophila melanogaster
• Sequence 2: XP_073792564.1
• Gene: dennd2db / 492474
• ZFINID: ZDB-GENE-041114-34
• Length: 524
• Species: Danio rerio
• Alignment Length: 469
• Identity: 111/469 - (23%)
• Similarity: 190/469 - (40%)
• Gaps: 92/469 - (19%)

  Fly    20 TPTPGLERGT----------------SSRSGGP-----AVPAG------------VIVES----- 46
            |||..::|..                .:::|.|     |.|||            ::|.|
Zfish    53 TPTDNVDRSAMKKISSMFSALQEKFQRAKAGAPTPAAVAPPAGRESHCGLRFFEYLLVVSLRKRS 117

  Fly    47 ------------FPEG------FRDQE--VLTGIPSFAFP-----CDTTSTSVQTYSFVHTTGDS 86
                        ||:.      .|:||  .:.....|.||     ...|..|.:|:|||.|..|.
Zfish   118 SGVGYEPQVTYQFPKREVMGRLQREQEEKSMKAAHLFCFPEGVHWAPVTEYSSETFSFVLTEVDG 182

  Fly    87 KWRFGFCR------QDPRTNTAMVLITYLPWHDTFLKLLPVLAELRRTDPNGFRTFLSEAYNQGI 145
            ..|.|:||      :..|...|..:|:::.....|.|:...:.:.|:........|:.......:
Zfish   183 SRRNGYCRRLLPAGKGARLPEAYCIISHVACFGLFSKIFDEVEKRRQISTAMIYPFMQSLREAPL 247

  Fly   146 PDCGGSLKV---YYSAGQSHFTFERPLQFQLPSMPENHNLNLYYNFVEPKEMIAVFAAMLAERRI 207
            |..|.::.:   ...||.......||..    |..|:.:....::.:..:|::.||.|.:.||||
Zfish   248 PSPGSTVSISSFIPDAGTQIIRLTRPAD----SWLEHVDFTALFSRLNDEELLLVFTAAVLERRI 308

  Fly   208 IFTSRHLDRLSSCIQAANAFLYPMVWQHIFIPVLPWEFKDYLGAPMPYLIGVPEPVLETVTSDEL 272
            ||.|..|..||..:.|..|.|||.||||.||.::|....|...||.|||:||.:.::..:|  :.
Zfish   309 IFISEELSTLSQVLHAVAALLYPFVWQHTFISIVPSVLIDVCEAPTPYLLGVQKSMMGLIT--DH 371

  Fly   273 GEVVILN----CDTKIFESPFDDVHNLPTEIVSQLKKHLN-HTH----DHIGDRISKIFLNALVQ 328
            .:|:|::    ..||......|:...||.::..:|...|: .||    :.:...:|:.||:..|:
Zfish   372 SDVMIVDLSTGAPTKFITRIGDEESLLPLKLKEELLSGLSARTHHASTEQLNRLVSEAFLSVFVK 436

  Fly   329 LIGGYRDAVEYHENSKTFNSQKFIES-RPAHLRPFLAKMMDLQIFAQFIDDRLTMLNSGLGFSDE 392
            .:|.:.:.::.....:.|..:.|::: .......|:...:..|:|..||.:..|..|.. ||
Zfish   437 TVGHFSEHIKRGGKPRQFQKKSFLKAVENKTYSSFVKLFIQTQMFDLFIQEEETQSNPN-GF--- 497

  Fly   393 FELETVRYAEKKKR 406
            |..:...:.::.|:
Zfish   498 FHRKVKEHRDRMKQ 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18659	NP_665880.2	uDENN	10..95	CDD:214824	32/143 (22%)
		DENN	98..282	CDD:460461	52/190 (27%)
		dDENN	315..379	CDD:129037	12/64 (19%)
dennd2db	XP_073792564.1	None