Protein Alignment CG18659 and Dennd2d

DIOPT Version :9

• Sequence 1: NP_665880.2
• Gene: CG18659 / 35929
• FlyBaseID: FBgn0027561
• Length: 908
• Species: Drosophila melanogaster
• Sequence 2: XP_006233176.1
• Gene: Dennd2d / 310772
• RGDID: 1305120
• Length: 476
• Species: Rattus norvegicus
• Alignment Length: 468
• Identity: 114/468 - (24%)
• Similarity: 191/468 - (40%)
• Gaps: 101/468 - (21%)

  Fly    23 PGLERGTSSRSGGPAVP-------------AG------------------------VIVESFPE- 49
            |.|..|.|..:.|.||.             ||                        .|...||:
  Rat    25 PRLRAGQSQNNPGDAVTEPERIQEHSPPIFAGGQHFFEYLLVVSLKKKHLGDDYEPTITYQFPKR 89

  Fly    50 -----GFRDQE--VLTGIPSFAFP-----CDTTSTSVQTYSFVHTTGDSKWRFGFCRQ------D 96
                 |.:::|  :|..||.|.||     ...|....:|:|||.|..|...:.|:||:      .
  Rat    90 ENLLRGQQEEEERLLKAIPLFCFPDGNEWAPLTEYPRETFSFVLTNVDGSRKIGYCRRLLPAGPG 154

  Fly    97 PRTNTAMVLITYLPWHDTFLKLL---------------PVLAELRRTD-PNGFRTFLSEAYNQGI 145
            ||......:|:.:.....|.|:|               |.:..||... |...:|...:::   |
  Rat   155 PRLPKVYCIISCIGCFGLFSKILDEVEKRHQISMAVIYPFMQGLREAAFPAPGKTVTLKSF---I 216

  Fly   146 PDCGGSLKVYYSAGQSHFTFERPLQFQLPSMPENHNLNLYYNFVEPKEMIAVFAAMLAERRIIFT 210
            ||          :|....:..|||...|    |:.:.:.....:..:::|.:||:.:.||:|||.
  Rat   217 PD----------SGTEFISLTRPLDSHL----EHVDFSALLQCLHFEQIIQIFASAVLERKIIFL 267

  Fly   211 SRHLDRLSSCIQAANAFLYPMVWQHIFIPVLPWEFKDYLGAPMPYLIGVPEPVLETVTSDELGEV 275
            :..|..||.||.||.|.|||..|.|.:|||:|......:..|.|:::||.....:.|....:.||
  Rat   268 AEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRFQQEVMDSPMEEV 332

  Fly   276 VILN-CDTKIFESPFDDVHNLP----TEIVSQLKKHLNH--THDHIGDRISKIFLNALVQLIGGY 333
            :::| |......|..|:...||    .:|:..|.:.:|.  |.:.|.:.:|..|:...|:.:|.|
  Rat   333 LLVNLCKGTFLLSVGDEKDILPRKLQDDILDSLAQGINELKTSEQINEHVSGPFVQFFVKTVGHY 397

  Fly   334 RDAVEYHENSK-TFNSQKFIESRPAHL-RPFLAKMMDLQIFAQFIDDRLTMLNSGLGFSDEFELE 396
            ...::...:.: .|..:.|.::..:.. |.|:.|.:..|:|:.||.:.....|...|:   |:.:
  Rat   398 ASYIKREASGQGHFQERSFCKAVTSKTKRRFVKKFVKTQLFSLFIQEAEKSRNPPAGY---FQKK 459

  Fly   397 TVRYAEKKKRGRN 409
            .:.|.|:||:.::
  Rat   460 ILEYEEQKKQKKS 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18659	NP_665880.2	uDENN	10..95	CDD:214824	29/121 (24%)
		DENN	98..282	CDD:280329	53/200 (27%)
		dDENN	315..379	CDD:129037	14/65 (22%)
Dennd2d	XP_006233176.1	uDENN	57..149	CDD:214824	21/91 (23%)
		DENN	156..340	CDD:280329	53/200 (27%)
		dDENN	379..444	CDD:129037	14/64 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810