Protein Alignment CG18659 and dennd2d

DIOPT Version :10

• Sequence 1: NP_665880.2
• Gene: CG18659 / 35929
• FlyBaseID: FBgn0027561
• Length: 908
• Species: Drosophila melanogaster
• Sequence 2: NP_001120238.1
• Gene: dennd2d / 100145288
• XenbaseID: XB-GENE-5816391
• Length: 458
• Species: Xenopus tropicalis
• Alignment Length: 437
• Identity: 108/437 - (24%)
• Similarity: 192/437 - (43%)
• Gaps: 65/437 - (14%)

  Fly    21 PTPGLERGTSSRSGGPAVPAGVIVESFPEGF----------------------RDQE--VLTGIP 61
            ||   ::.|...|||.:....::|.|..:.:                      :|:|  :|..||
 Frog    34 PT---DQKTLVLSGGQSFFEYLVVVSLKKNYDGNYAPQITYQFPKLENILHFQKDEEERLLNAIP 95

  Fly    62 SFAFPCDTT-----STSVQTYSFVHTTGDSKWRFGFCRQ------DPRTNTAMVLITYLPWHDTF 115
            .|.||...|     ..:.:|:|||.|..||..:||:||:      ..|:.....:|:.|.....|
 Frog    96 LFCFPDGNTWAPLKEYTSETFSFVLTNIDSSRKFGYCRRLLPAGNGSRSPEVYCIISSLGCFGLF 160

  Fly   116 LKLLPVLAELRRTDPNGFRTFLSEAYNQGI-----PDCGGSLKV---YYSAGQSHFTFERPLQFQ 172
            .|:|..:.:.|.     ..|.|...:.||:     |..|.::|:   ...:|.......|||..:
 Frog   161 AKILDEVEKRRE-----IATALIYPFMQGLREATFPAPGKTVKIKSFIPESGTEIIELTRPLDCR 220

  Fly   173 LPSMPENHNLNLYYNFVEPKEMIAVFAAMLAERRIIFTSRHLDRLSSCIQAANAFLYPMVWQHIF 237
            |    |:.:.......:..:.::.:||:::.|||:|..:|.|..||.||.|..|.|||..|:|.:
 Frog   221 L----EHIDFKTLLQCLNSQIILHIFASVVLERRVILVARDLSILSECIHAVVALLYPFAWEHTY 281

  Fly   238 IPVLPWEFKDYLGAPMPYLIGVPEPVLETVTSDELGEVVILN-CDTKIFESPFDDVHNLPTEIVS 301
            |||||....|.:..|.|:::||....|..:....:.||:::: |..::.:...|:...||.::..
 Frog   282 IPVLPHVLIDTVSCPAPFIVGVQNQFLSHILDQPMEEVLLVDLCKGELIQKVGDEEKILPPKLQE 346

  Fly   302 QLK------KHLNHTHDHIGDRISKIFLNALVQLIGGYRDAV-EYHENSKTFNSQKFIES-RPAH 358
            |::      :.:..|...|...:||.|:...::::|.|...: |.:....||..:.|::: ....
 Frog   347 QIRISLDDYQQITKTTPEINTAVSKTFMQFFMKVMGHYTSHLQEINVGKFTFQEKAFLKAIHSKT 411

  Fly   359 LRPFLAKMMDLQIFAQFIDDRLTMLNSGLGFSDEF-ELETVRYAEKK 404
            :|.||...:..|:|:.||:.:.......:.|..:. |....|..|:|
 Frog   412 IRRFLKCFVKTQMFSIFIEAQQNKSTQNVYFQQKVKEFNEQRKPERK 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18659	NP_665880.2	uDENN	10..95	CDD:214824	27/102 (26%)
		DENN	98..282	CDD:460461	53/192 (28%)
		dDENN	315..379	CDD:129037	16/65 (25%)
dennd2d	NP_001120238.1	uDENN	45..136	CDD:214824	23/90 (26%)
		DENN	143..327	CDD:460461	53/192 (28%)
		dDENN	366..430	CDD:129037	15/63 (24%)