DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE13 and CAM1

DIOPT Version :9

Sequence 1:	NP_001188889.1	Gene:	GstE13 / 35928	FlyBaseID:	FBgn0033381	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_015277.1	Gene:	CAM1 / 856059	SGDID:	S000005969	Length:	415	Species:	Saccharomyces cerevisiae

Alignment Length:	217	Identity:	55/217 - (25%)
Similarity:	96/217 - (44%)	Gaps:	33/217 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKPTLY--YALFSPPARACILVAKLIGLDLELKPVDFAKKEHLSEEFVKLNPQHQIPVFVDSDG 63
            ||:.|||  :.:.:...|..:   |.:.||:::...|.|     :|:|.:..|..::|.||...|
Yeast     1 MSQGTLYANFRIRTWVPRGLV---KALKLDVKVVTPDAA-----AEQFARDFPLKKVPAFVGPKG 57

  Fly    64 EVYVDSHAIVCFLVAKYAGNDQLYPR------DLKRRAHIDHRMHYENGVL-FQVVKDIVARNIY 121
            ....::.||..:|| |.:.:|::..:      ||..:|.|.......|..| .|:...||.  :.
Yeast    58 YKLTEAMAINYYLV-KLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVP--LK 119

  Fly   122 GGEGEYNPRSLTLCHNAYSDL----EHFLQQGSFVVGNELSVADV---SIHTTLVTLDLLIPVE- 178
            || ..||.:|:....:|...:    |:.|:..:::....:|:||:   ||.|..  .:.|...|
Yeast   120 GG-APYNKKSVDSAMDAVDKIVDIFENRLKNYTYLATENISLADLVAASIFTRY--FESLFGTEW 181

  Fly   179 REKYPQTKQWME--RMDKLLPD 198
            |.::|...:|..  |....|.|
Yeast   182 RAQHPAIVRWFNTVRASPFLKD 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE13	NP_001188889.1	GST_N_Delta_Epsilon	4..78	CDD:239343	19/75 (25%)
GstE13	NP_001188889.1	GST_C_Delta_Epsilon	92..211	CDD:198287	29/118 (25%)
CAM1	NP_015277.1	GST_N_EF1Bgamma	4..73	CDD:239342	20/77 (26%)
		GST_C_EF1Bgamma_like	92..214	CDD:198290	29/117 (25%)
		EF1G	255..359	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740