DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE13 and GstD5

DIOPT Version :9

Sequence 1:	NP_001188889.1	Gene:	GstE13 / 35928	FlyBaseID:	FBgn0033381	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_524914.3	Gene:	GstD5 / 48338	FlyBaseID:	FBgn0010041	Length:	216	Species:	Drosophila melanogaster

Alignment Length:	213	Identity:	70/213 - (32%)
Similarity:	118/213 - (55%)	Gaps:	20/213 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YYALFSPPARACILVAKLIGLDLELKPVDFAKKEHLSEEFVKLNPQHQIPVFVDSDGEVYVDSHA 71
            ||:......|..|:|||.:|:.|.:|.::..:|:.|..|||||||||.||..||:...:: :|.|
  Fly     4 YYSPRGSGCRTVIMVAKALGVKLNMKLLNTLEKDQLKPEFVKLNPQHTIPTLVDNGFSIW-ESRA 67

  Fly    72 IVCFLVAKYAGNDQLYPRDLKRRAHIDHRMHYENGVLFQVVKDIVARNIY--------GGEGEYN 128
            |..:||.||..:|.|:|:|.|::|.::.|::::.|.|:    |..|:..|        |.:.::.
  Fly    68 IAVYLVEKYGKDDTLFPKDPKKQALVNQRLYFDMGTLY----DSFAKYYYPLFHTGKPGSDEDFK 128

  Fly   129 PRSLTLCHNAYSDLEHFLQQGSFVVGNELSVADVSIHTTLVTLDLLIPVEREKYPQTKQWMERMD 193
            .     ..:::..|..||:..::|.|:.|:|||::|.:|:.|.: :...:..|||...:|.....
  Fly   129 K-----IESSFEYLNIFLEGQNYVAGDHLTVADIAILSTVSTFE-IFDFDLNKYPNVARWYANAK 187

  Fly   194 KLLPDNEEINLKGARALQ 211
            |:.|..|| |.|||..|:
  Fly   188 KVTPGWEE-NWKGAVELK 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE13	NP_001188889.1	GST_N_Delta_Epsilon	4..78	CDD:239343	29/70 (41%)
GstE13	NP_001188889.1	GST_C_Delta_Epsilon	92..211	CDD:198287	33/126 (26%)
GstD5	NP_524914.3	GstA	1..184	CDD:223698	61/190 (32%)
		GST_N_Delta_Epsilon	1..74	CDD:239343	29/70 (41%)
		GST_C_Delta_Epsilon	88..204	CDD:198287	33/126 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460229
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	10	9.900