DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstE13 and GSTZ1

DIOPT Version :9

Sequence 1:	NP_001188889.1	Gene:	GstE13 / 35928	FlyBaseID:	FBgn0033381	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_001350632.1	Gene:	GSTZ1 / 2954	HGNCID:	4643	Length:	217	Species:	Homo sapiens

Alignment Length:	207	Identity:	57/207 - (27%)
Similarity:	93/207 - (44%)	Gaps:	35/207 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KPTLY-YALFSPPARACILVAKLIGLDLELKPVDFAKK--EHLSEEFVKLNPQHQIPVFVDSDGE 64
            ||.|| |...|...|..|.:| |.|:|.|..|::..|.  :..|::|..|||..|:|. :..||.
Human     6 KPILYSYFRSSCSWRVRIALA-LKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPT-LKIDGI 68

  Fly    65 VYVDSHAIVCFLVAKYAGNDQLYPRDLKRRAHIDHRMHYENGVLFQVVKDIVARNIYGGE----- 124
            ....|.||:.:| .:.....:|.|:|.|:||.:            :::.|::|..|...:
Human    69 TIHQSLAIIEYL-EEMRPTPRLLPQDPKKRASV------------RMISDLIAGGIQPLQNLSVL 120

  Fly   125 ---GEYNPRSLTLCHNA----YSDLEHFLQQ--GSFVVGNELSVADVSIHTTLVTLDLLIPVERE 180
               ||  ...||...||    ::.||..||.  |.:.||:|:::||:.:...:...: ...|:..
Human   121 KQVGE--EMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAE-RFKVDLT 182

  Fly   181 KYPQTKQWMERM 192
            .||......:|:
Human   183 PYPTISSINKRL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE13	NP_001188889.1	GST_N_Delta_Epsilon	4..78	CDD:239343	27/76 (36%)
GstE13	NP_001188889.1	GST_C_Delta_Epsilon	92..211	CDD:198287	26/115 (23%)
GSTZ1	NP_001350632.1	maiA	8..212	CDD:273527	55/205 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810