Protein Alignment GstE13 and GSTT4

DIOPT Version :10

• Sequence 1: NP_610457.1
• Gene: GstE13 / 35928
• FlyBaseID: FBgn0033381
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_001345593.1
• Gene: GSTT4 / 25774
• HGNCID: 26930
• Length: 241
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 59/250 - (23%)
• Similarity: 100/250 - (40%)
• Gaps: 60/250 - (24%)

  Fly     6 LYYALFSPPARACILVAKLIGLDLELKPVDFAKKEHLSEEFVKLNPQHQIPVFVDSDGE-VYVDS 69
            ||..|.|.|.||..:.:|...:....:.||..|..|.|:.::.:||..::|..  .||: :..:|
Human     5 LYMDLLSAPCRAVYIFSKKHDIQFNFQFVDLLKGHHHSKGYIDINPLRKLPSL--KDGKFILSES 67

  Fly    70 HAIVCFLVAKYAGNDQLYPRDLKRRAHIDHRMHYENGVLFQVVKDIV-----ARNIYGGE----- 124
            .||:.:|..||:......|.|...||.:|..:.:::......:|.||     ...|.|.|
Human    68 AAILYYLCRKYSAPSHWCPPDPHARARVDEFVAWQHTAFQLPMKKIVWLKLLIPKITGEEVSAEK 132

  Fly   125 ----GEYNPRSLTLCHNAYSDLEHFLQQGSFVVGNELSVADVSIHTTLVTLDLLIPVE------- 178
                .|....||.|..      |:|||...|:.||::|:||:     :..::::.|:.
Human   133 MEHAVEEVKNSLQLFE------EYFLQDKMFITGNQISLADL-----VAVVEMMQPMAANYNVFL 186

  Fly   179 ---------------------REKYPQTKQ---W-MERMDKLLPDNEEINLKGAR 208
                                 ||.:.:..|   | ...:|.::.:|....||.:|
Human   187 NSSKLAEWRMQVELNIGSGLFREAHDRLMQLADWDFSTLDSMVKENISELLKKSR 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE13	NP_610457.1	GstA	5..192	CDD:440390	54/232 (23%)
GSTT4	NP_001345593.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..78	CDD:469754	22/74 (30%)
		GST_C_Theta	91..217	CDD:198292	26/136 (19%)