DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstE13 and Gdap1

DIOPT Version :9

Sequence 1:	NP_001188889.1	Gene:	GstE13 / 35928	FlyBaseID:	FBgn0033381	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_034397.1	Gene:	Gdap1 / 14545	MGIID:	1338002	Length:	358	Species:	Mus musculus

Alignment Length:	216	Identity:	44/216 - (20%)
Similarity:	81/216 - (37%)	Gaps:	52/216 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LYYALFSPPARACILVAKLIGLDLELKPVDFAKKEHLSEEFVKLNPQHQIPVFVDSDGEVYVDSH 70
            ||:...|..::...||.....|..|...|.....||....|::||...::||.|..: .:..::.
Mouse    28 LYHWTHSFSSQKVRLVIAEKALKCEEHDVSLPLSEHNEPWFMRLNSAGEVPVLVHGE-NIICEAT 91

  Fly    71 AIVCFLVAKYAGNDQLYPRDLKRRAHIDHRMHYENGVLFQVVKDIVARNIYGGEGE-YNPRSLTL 134
            .|:.:|...:.  |:..||                              :...||. |.||   :
Mouse    92 QIIDYLEQTFL--DERTPR------------------------------LMPDEGSMYYPR---V 121

  Fly   135 CHNAYSDLEHFLQQGSFVVGNELSVADVSIHTTLVTLDLLIPVE-----REKYPQTKQWMERMDK 194
            .|  |.:|...|...::..|       ..:|..| |:|.:||..     |.:...|:..::::.:
Mouse   122 QH--YRELLDSLPMDAYTHG-------CILHPEL-TVDSMIPAYATTRIRSQIGNTESELKKLAE 176

  Fly   195 LLPDNEEINLKGARALQTRIL 215
            ..||.:|..:...:.|::::|
Mouse   177 ENPDLQEAYIAKQKRLKSKLL 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstE13	NP_001188889.1	GST_N_Delta_Epsilon	4..78	CDD:239343	18/71 (25%)
GstE13	NP_001188889.1	GST_C_Delta_Epsilon	92..211	CDD:198287	21/124 (17%)
Gdap1	NP_034397.1	GST_N_GDAP1	26..98	CDD:239350	17/70 (24%)
		GST_C_GDAP1	179..289	CDD:198336	5/19 (26%)
		Required for mitochondrial localization. /evidence=ECO:0000250	320..358
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840