Protein Alignment GstE13 and CLIC1

DIOPT Version :10

• Sequence 1: NP_610457.1
• Gene: GstE13 / 35928
• FlyBaseID: FBgn0033381
• Length: 226
• Species: Drosophila melanogaster
• Sequence 2: NP_001279.2
• Gene: CLIC1 / 1192
• HGNCID: 2062
• Length: 241
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 54/248 - (21%)
• Similarity: 88/248 - (35%)
• Gaps: 80/248 - (32%)

  Fly    13 PPARACILVAKLIGLDLELKPVDFAKKEHLSEEFVKLNPQHQIPVFVDSDGEVYVDSHAIVCFL- 76
            |.::...:|..|.|:...:..||..::   :|...||.|..|:| |:....||:.|::.|..||
Human    25 PFSQRLFMVLWLKGVTFNVTTVDTKRR---TETVQKLCPGGQLP-FLLYGTEVHTDTNKIEEFLE 85

  Fly    77 -------------------------VAKYAG---------NDQLYPRDLKRRAHIDHRMHYENGV 107
                                     .||::.         ||.|....||....:|   :|....
Human    86 AVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLD---NYLTSP 147

  Fly   108 LFQVVKDIVARNIYGGEGEYNPRSLTLCHNAYSDLEHFLQQGSFVVGNELSVADVSIHTTLVTLD 172
            |.:.|.:..|.:    ||                    :.|..|:.||||::||.::...|..:.
Human   148 LPEEVDETSAED----EG--------------------VSQRKFLDGNELTLADCNLLPKLHIVQ 188

  Fly   173 LLIPVER-----------EKYPQTKQWMERMDKLLPDNEEINL---KGARALQ 211
            ::....|           .:|.......|......||:|||.|   :.|:||:
Human   189 VVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstE13	NP_610457.1	GstA	5..192	CDD:440390	45/224 (20%)
CLIC1	NP_001279.2	Required for insertion into the membrane	2..90		19/68 (28%)
		O-ClC	6..241	CDD:129941	53/246 (22%)
		G-site. /evidence=ECO:0000305|PubMed:25581026	24..27		1/1 (100%)