Protein Alignment Su(var)2-10 and pias2

DIOPT Version :9

• Sequence 1: NP_724749.1
• Gene: Su(var)2-10 / 35927
• FlyBaseID: FBgn0003612
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_031757544.1
• Gene: pias2 / 779910
• XenbaseID: XB-GENE-988474
• Length: 621
• Species: Xenopus tropicalis
• Alignment Length: 622
• Identity: 238/622 - (38%)
• Similarity: 332/622 - (53%)
• Gaps: 72/622 - (11%)

  Fly    43 KECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTNLE-LLAPKVQEVYAQSVQEQN 106
            :|...||...||.|||.:|.|...:.:|||.||..|.|..|:.... .:..|::|:|.:......
 Frog     5 EELRNMVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKNGCSPAVQIKIKELYRRRFPRTL 69

  Fly   107 ATLQYIDPTR--------------------MYSHIQLPPT-VQP-NPVGLVGSGQGVQVPGGQMN 149
            ..:..:.|.|                    |:|   ||.| |.| :|...:||   |.:...:
 Frog    70 DGVTGLAPIRSNVFNLDSSAPVDPDLAVSGMHS---LPSTSVSPCSPASPLGS---VLLQDTK-- 126

  Fly   150 VVGGAPFLHTHSINSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQA 214
                |||.......|..|:||||.||.|.|||||..||||::||....||.||..|.|.|||||.
 Frog   127 ----APFEIQQLSPSIPPVHPDVHLKSLPFYDVLDVLIKPTSLVQNTLQRFQEKFFIFALTPQQV 187

  Fly   215 TEIASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVE 279
            .|:..:||.....:.::::|||||.||.||||.|||.:|.::.:|||.||..||......:..||
 Frog   188 REVVISRDYMPGGRRDYSVQVQLRLCLAETSCPQEDNYPSSLCIKVNGKLFPLPGCAVPPKNGVE 252

  Fly   280 PKRPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADY 344
            .|||.||:|:||.|:||..|.|.:::.|..:..::|.::||||::|||..|||::|.||::..|:
 Frog   253 QKRPGRPLNITSLVRLSSAVPNQVSISWASEIGKNYSMSVYLVRQLTSAVLLQKLKMKGIRNPDH 317

  Fly   345 TRGLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTW 409
            :|.|||||||.|.|.|||||.|:|||.||||||::.:||||.||||||||||:|||||||:||||
 Frog   318 SRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAVTCSHLQCFDAALYLQMNEKKPTW 382

  Fly   410 NCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTPSKPAQK 474
            .||||||.|.|::|:|||.|.|:|...   ||..||:..|||||..  :|.:.:.:.:||.....
 Frog   383 ICPVCDKKASYESLIIDGLFMEILNQC---SDVDEIKFQQDGSWCP--MRPKKEPMTSPSTQYPH 442

  Fly   475 VEVISDDIELISDDAKPVKRDLSPAQDEQPTSTSNSETVDLTL-SDSDDDMPLAKRRPPAKQAVA 538
            :|           .|..:.:..|..:..:.|..:.:|.:|||| |.||||      .||||:...
 Frog   443 IE-----------GAGVISKICSAVEGGETTRKNKAEVIDLTLESSSDDD------EPPAKKECV 490

  Fly   539 SSTSNGSGG--GQRAYTPAQQPQQSESPEQQASRQSPEKQTVSEQQLQQQQH-EQPATAAVHASL 600
            ..|.:....  |..:|.|        |..:.......|.:.:.........| ..||.|.:.|.|
 Frog   491 YLTESQEAAMKGVLSYQP--------SSIRVGKVAGIESEPMHPSMAGYADHFHHPAIAGISAEL 547

  Fly   601 --LESLAAAVAD-QKHFQLLDLAAVAAAAAATASSGQ 634
              |:.|:....| |:::..:.|.::.:|...:..:|:
 Frog   548 PGLDFLSLVSMDPQQYYPPMFLDSLTSAMPTSHVTGK 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-10	NP_724749.1	SAP	49..83	CDD:128789	15/33 (45%)
		PINIT	171..307	CDD:291022	67/135 (50%)
		zf-MIZ	368..417	CDD:280964	39/48 (81%)
pias2	XP_031757544.1	SAP	11..45	CDD:128789	15/33 (45%)
		PINIT	146..295	CDD:405075	69/148 (47%)
		SP-RING_PIAS	342..389	CDD:319704	37/46 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	178	1.000	Domainoid score	I3491
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	390	1.000	Inparanoid score	I1954
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1205949at2759
OrthoFinder	1	1.000	-	-		FOG0000526
OrthoInspector	1	1.000	-	-		otm47702
Panther	1	1.100	-	-	O	PTHR10782
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X350
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.160