Protein Alignment Su(var)2-10 and pias1a

DIOPT Version :10

• Sequence 1: NP_724749.1
• Gene: Su(var)2-10 / 35927
• FlyBaseID: FBgn0003612
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_692921.4
• Gene: pias1a / 564496
• ZFINID: ZDB-GENE-120727-5
• Length: 651
• Species: Danio rerio
• Alignment Length: 617
• Identity: 249/617 - (40%)
• Similarity: 345/617 - (55%)
• Gaps: 91/617 - (14%)

  Fly    44 ECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTNLE-LLAPKVQEVYAQSVQEQNA 107
            |.:|||..|||.|||.:|.:...:..|||.:|.::.|..|:.... .:..|::|:|.:..
Zfish     6 ELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRF----- 65

  Fly   108 TLQYIDPTRMYSHIQLP-PTVQPN---PVGLVGSG-QGVQVPGGQM---NVVG-----GAPFLHT 159
                  ||::.|..:|. |.|.|.   |.||...| .|...|...:   :::|     |.|.|.|
Zfish    66 ------PTKLVSPAELALPGVHPAASLPPGLTQLGFDGHGAPPSPLLPISLLGPKHELGLPHLPT 124

  Fly   160 --HSINSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATEIASNRD 222
              |      |:||||:|::|.|||:|..||||::|...|:||.||..|.|.|||||..:::|:.|
Zfish   125 NLH------PVHPDVKLQRLPFYDLLDELIKPTSLASDNSQRFQETCFAFALTPQQVQQVSSSMD 183

  Fly   223 IRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPV 287
            | :.:|.:..:||||||||.||||.|||.||||:.||||.|.|.||..:|..:..||||||.||:
Zfish   184 I-SGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPI 247

  Fly   288 NVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEK 352
            |:||.::||.||.|||.|.|..:..|||.|||||||:|:||.||||::.||::..|::|.|||||
Zfish   248 NITSLIRLSTTVPNTIVVSWTSEIGRSYSLAVYLVKQLSSTMLLQRLRGKGIRNPDHSRALIKEK 312

  Fly   353 LTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDKP 417
            ||.|.|.|||||.|:|||.||||||::::||||.||||||||||:||:||||:||||.||||||.
Zfish   313 LTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKK 377

  Fly   418 AIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTPSKPAQKVEVISDDI 482
            |.|::|:|||.|.|:|.|.|   |..|||..:||||:             |.:..::|:.:|...
Zfish   378 APYEHLIIDGLFMEILNSCL---DCDEIQFKEDGSWA-------------PMRSKKEVQEVSASY 426

  Fly   483 ELISDDAKPVKRDLSPAQDEQPTSTSNS------ETVDLTLSDS----DDDMPLAKRRPPAKQAV 537
            ..|....:....:    |:.|...:|..      |.:||||..|    :|:.||.|:..|:..::
Zfish   427 NGIDGGCRTSVLE----QNSQTNGSSGGGNRKKVEVIDLTLDSSSEEEEDEEPLPKKSCPSLSSL 487

  Fly   538 ASSTSNGSGGGQRAYTPAQQPQQSESPEQQASRQSPEKQTVSEQQ-----------------LQQ 585
            :....||.....|..:|..  :....|:...|...|....:.:.:                 ||.
Zfish   488 SPQMDNGVLNLHRQASPVS--RTPSMPQVDTSYIPPPPPLIQDYRHYYSTPTELSDLNFFPFLQG 550

  Fly   586 QQHEQPATAAVHASLLESLAAAVADQKHFQLL 617
            :.|:       |.:::.: |||.|.:.|..||
Zfish   551 ENHQ-------HYNMVMA-AAASASEDHDLLL 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-10	NP_724749.1	SAP	49..83	CDD:128789	13/33 (39%)
		PINIT	175..323	CDD:464136	82/147 (56%)
		SP-RING_PIAS	369..416	CDD:438444	36/46 (78%)
pias1a	XP_692921.4	None