Protein Alignment Su(var)2-10 and pias2

DIOPT Version :10

• Sequence 1: NP_724749.1
• Gene: Su(var)2-10 / 35927
• FlyBaseID: FBgn0003612
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_005165453.2
• Gene: pias2 / 564149
• ZFINID: ZDB-GENE-060424-1
• Length: 624
• Species: Danio rerio
• Alignment Length: 629
• Identity: 236/629 - (37%)
• Similarity: 329/629 - (52%)
• Gaps: 69/629 - (10%)

  Fly    43 KECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTNL-ELLAPKVQEVYAQSVQEQN 106
            :|...||...||.|||.:|.|...:.:|||.:|..|.|..||:.. ..:..|::|:|.:......
Zfish     5 EELRNMVSSFRVSELQVLLGFAGRNKSGRKHELLLRALHLLRSGCSSAVQIKIKELYRRRYPRTF 69

  Fly   107 ATLQYI----DPTRMYSHIQLPPTVQPNPVGLVGSGQGVQVPGGQMNVVG------GAPFLHTHS 161
            ..||.:    ...:.:.|:.         .|.......:.:|....:|:.      .:|..|...
Zfish    70 EGLQDLAALKSSIKSFIHLD---------SGATAVSSDLTLPTDHSDVLQQRRESCDSPVFHESK 125

  Fly   162 --INSQ------LPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRV-QEVPFYFTLTPQQATEI 217
              :|.|      .|:||||::|.|.|||||..|||||:|.....||. .|..|.|.|||||..|:
Zfish   126 PMMNMQQPTTLMAPVHPDVQMKSLPFYDVLDVLIKPSSLGAHAVQRFHNEKYFIFALTPQQVREV 190

  Fly   218 ASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKR 282
            ..:||.....:.::.:|:||||||.||||.|||.:|..:.:|||.||..||...|..:..||.||
Zfish   191 CISRDFLPGGRRDYMVQIQLRFCLAETSCPQEDNYPNGLCIKVNGKLFPLPGFAPPPKNGVEQKR 255

  Fly   283 PPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRG 347
            |.||:|:||.|:||..|.|.|.|.|.|:..::|.::||||::|||..||||::.||::..|::|.
Zfish   256 PGRPLNITSLVRLSSAVPNQIVVTWAPEIGKTYSMSVYLVRQLTSPLLLQRLRMKGIRNPDHSRA 320

  Fly   348 LIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCP 412
            |||||||.|.|.|||||.|:|||.||||||::.:||||.||||||||||:|||||||:||||.||
Zfish   321 LIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTVPCRAVTCSHLQCFDAALYLQMNEKKPTWICP 385

  Fly   413 VCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTPSKPAQKVEV 477
            ||||.|.|::|:|||.|.|:|...   :|..|||..:||:|.....:.||..|.:|.  ..|:
Zfish   386 VCDKKATYESLIIDGLFMEILNDC---TDVDEIQFQEDGTWCPMRPKKETLKLSSPC--ISKI-- 443

  Fly   478 ISDDIELISDDAKPVKRDLSPAQDEQPTSTSNSETVDLTL----SDSDDDMPLAKRRPPAKQAVA 538
                     |.:.||::....:..| .:||..::.:||||    .|.:||.||.||     ....
Zfish   444 ---------DCSVPVRQSAVVSVPE-TSSTKKADVIDLTLESSSDDEEDDPPLKKR-----CIYM 493

  Fly   539 SSTSNGSGGGQRAYTPAQQPQQSESPEQQASRQSPEKQTVSEQQLQQQQHEQPATAAVHASLLES 603
            |........|...|    ||.....|..|:...|....::::..: ...|...:|.......|:.
Zfish   494 SKAEEMHSKGVLTY----QPSTVRVPNVQSLDTSYLTSSIADYSV-PFHHSSLSTIPTDMQSLDL 553

  Fly   604 LAAAVAD-QKHFQ---LLD-----LAAVAAAAAATASSGQSQNA 638
            .:....| |:||:   .||     |.:...:|:..:||.|.:.|
Zfish   554 FSLIQGDPQQHFRGPIFLDSLSSSLQSATTSASLVSSSAQYETA 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-10	NP_724749.1	SAP	49..83	CDD:128789	14/33 (42%)
		PINIT	175..323	CDD:464136	72/148 (49%)
		SP-RING_PIAS	369..416	CDD:438444	37/46 (80%)
pias2	XP_005165453.2	None