Protein Alignment Su(var)2-10 and Zmiz1

DIOPT Version :9

• Sequence 1: NP_724749.1
• Gene: Su(var)2-10 / 35927
• FlyBaseID: FBgn0003612
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: NP_001101863.1
• Gene: Zmiz1 / 361103
• RGDID: 1311620
• Length: 1072
• Species: Rattus norvegicus
• Alignment Length: 605
• Identity: 139/605 - (22%)
• Similarity: 211/605 - (34%)
• Gaps: 188/605 - (31%)

  Fly   100 QSVQEQNATLQYIDPT-------------------------RMYSH--IQLPPTVQPNPVG---- 133
            |.:..|.:|.||..||                         ..||.  :..||  :|.||.
  Rat   454 QRMPSQPSTGQYPPPTVNMGQYYKPEQFNGQNNTFSSGSSYSSYSQGSVNRPP--RPVPVANYPH 516

  Fly   134 --LVGSGQGVQVPGGQMNVVGGAPFLHTHSINSQLPIHPDVRLKKLAFYDVLGTLIKP--STLVP 194
              :.|:......||..:     .|:| :.|.:.:.|..||               |||  |.|.|
  Rat   517 SPVPGNPTPPMTPGSSI-----PPYL-SPSQDVKPPFPPD---------------IKPNMSALPP 560

  Fly   195 RNTQRVQEVPFYFTLTPQQATEIASNRD--IRNSSKVEHAIQV-----QLRFCLVETSCDQED-- 250
            .......|:...|.:           ||  :....::||.:.|     .||..:.:|...:.|
  Rat   561 PPANHNDELRLTFPV-----------RDGVVLEPFRLEHNLAVSNHVFHLRPTVHQTLMWRSDLE 614

  Fly   251 ----CF-----------PPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKL----- 295
                |:           |.:|.|.|                |..|....|..|.||:..|
  Rat   615 LQFKCYHHEDRQMNTNWPASVQVSV----------------NATPLTIERGDNKTSHKPLHLKHV 663

  Fly   296 -SP---TVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKL--- 353
             .|   |:..|:|...|     |:...:.||.:.:...:||.:..|.:.||::....||...
  Rat   664 CQPGRNTIQITVTACCC-----SHLFVLQLVHRPSVRSVLQGLLKKRLLPAEHCITKIKRNFSSV 723

  Fly   354 -------TEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNC 411
                   |.:.:..:..|.:||||.||:...::.||.|...|.|:||||...|||:|..:.||.|
  Rat   724 AASSGNTTLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCKHVQCFDLESYLQLNCERGTWRC 788

  Fly   412 PVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTPSKPAQKVE 476
            |||:|.|:.:.|.:|.|...:| :::..|:..|:.:....||....::|:..|.|.|
  Rat   789 PVCNKTALLEGLEVDQYMWGIL-NAIQHSEFEEVTIDPTCSWRPVPIKSDLHIKDDP-------- 844

  Fly   477 VISDDIELISDDAKPVKR--DLSPAQDEQPTSTSNSETVDLTLSDSDDDMPLAKRRPPAKQAVAS 539
                       |..|.||  .:||:|...|    |...:...|.......||    ||.....:|
  Rat   845 -----------DGIPSKRFKTMSPSQMIMP----NVMEMIAALGPGPSPYPL----PPPPGGTSS 890

  Fly   540 S--TSNGSG--------------GGQR----AYTPAQQPQQSESPEQQASRQSPEKQTVSEQQLQ 584
            :  :|.||.              ||..    .:.|.|.....:.|...|:.:.|....:.|....
  Rat   891 NDYSSQGSNYQGHGNFDFPHGNPGGTSMNDFMHGPPQLSHPPDMPNNMAALEKPLSHPMQETMPH 955

  Fly   585 QQQHEQPATAAVHASLLESL 604
            ....:||     |.|:.:.|
  Rat   956 AGSSDQP-----HPSIQQGL 970

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-10	NP_724749.1	SAP	49..83	CDD:128789
		PINIT	171..307	CDD:291022	34/170 (20%)
		zf-MIZ	368..417	CDD:280964	24/48 (50%)
Zmiz1	NP_001101863.1	Zmiz1_N	8..100	CDD:375500
		PHA03247	<183..562	CDD:223021	29/130 (22%)
		SP-RING_ZMIZ	746..793	CDD:319705	23/46 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810