Sequence 1: | NP_724749.1 | Gene: | Su(var)2-10 / 35927 | FlyBaseID: | FBgn0003612 | Length: | 640 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_899031.2 | Gene: | Zmiz1 / 328365 | MGIID: | 3040693 | Length: | 1072 | Species: | Mus musculus |
Alignment Length: | 605 | Identity: | 135/605 - (22%) |
---|---|---|---|
Similarity: | 208/605 - (34%) | Gaps: | 188/605 - (31%) |
- Green bases have known domain annotations that are detailed below.
Fly 100 QSVQEQNATLQYIDPT-------------------------RMYSH--IQLPPTVQPNPVG---- 133
Fly 134 --LVGSGQGVQVPGGQMNVVGGAPFLHTHSINSQLPIHPDVRLKKLAFYDVLGTLIKP--STLVP 194
Fly 195 RNTQRVQEVPFYFTLTPQQATEIASNRD--IRNSSKVEHAIQV-----QLRFCLVETSCDQED-- 250
Fly 251 ----CF-----------PPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKL----- 295
Fly 296 -SP---TVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKL--- 353
Fly 354 -------TEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNC 411
Fly 412 PVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILDTPSKPAQKVE 476
Fly 477 VISDDIELISDDAKPVKR--DLSPAQDEQPTSTSNSETVDLTLSDSDDDMPLAKRRPPAKQAVAS 539
Fly 540 STSNGSGGGQRA--------------------YTPAQQPQQSESPEQQASRQSPEKQTVSEQQLQ 584
Fly 585 QQQHEQPATAAVHASLLESL 604 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Su(var)2-10 | NP_724749.1 | SAP | 49..83 | CDD:128789 | |
PINIT | 171..307 | CDD:291022 | 34/170 (20%) | ||
zf-MIZ | 368..417 | CDD:280964 | 24/48 (50%) | ||
Zmiz1 | NP_899031.2 | Sufficient for transactivation activity, sufficient for interaction with NOTCH1. /evidence=ECO:0000250|UniProtKB:Q9ULJ6 | 1..120 | ||
Zmiz1_N | 8..100 | CDD:375500 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 112..141 | ||||
PHA03247 | <119..546 | CDD:223021 | 20/99 (20%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 362..538 | 19/91 (21%) | |||
SP-RING_ZMIZ | 746..793 | CDD:319705 | 23/46 (50%) | ||
Transactivation domain. /evidence=ECO:0000250|UniProtKB:Q9ULJ6 | 844..1072 | 28/159 (18%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 875..1072 | 17/105 (16%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG2169 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3884 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.840 |