Protein Alignment Su(var)2-10 and pias1

DIOPT Version :9

• Sequence 1: NP_724749.1
• Gene: Su(var)2-10 / 35927
• FlyBaseID: FBgn0003612
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_002932990.1
• Gene: pias1 / 100488714
• XenbaseID: XB-GENE-486558
• Length: 648
• Species: Xenopus tropicalis
• Alignment Length: 653
• Identity: 254/653 - (38%)
• Similarity: 358/653 - (54%)
• Gaps: 106/653 - (16%)

  Fly    44 ECEQMVQMLRVVELQKILSFLNISFAGRKTDLQSRILSFLRTNLE-LLAPKVQEVYAQSVQEQNA 107
            |.:|||..|||.|||.:|.:...:..|||.:|.::.|..|:|... .:..|::|:|     .:..
 Frog     6 ELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKTGCSPAVQMKIKELY-----RRRF 65

  Fly   108 TLQYIDPT-----RMYSH---IQLPPTVQPN-------------PVGLVGSGQGVQVPGGQMNVV 151
            .|:.:.|.     .::|.   :.|.|:..|.             ||.|        :|..::::.
 Frog    66 PLKILTPADFSLPSVHSSSMPVNLSPSSIPQLSYDGHPASSPLMPVSL--------LPKHELDLP 122

  Fly   152 GGAPFLHTHSINSQLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATE 216
            ..|..||        |:||||:|:||.|||:|..||||::|...|:||.||..|.|.|||||..:
 Frog   123 HLASNLH--------PVHPDVKLQKLPFYDLLDELIKPTSLASDNSQRFQETCFAFALTPQQVQQ 179

  Fly   217 IASNRDIRNSSKVEHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPK 281
            |:|:.|| :.:|.:..:||||||||.||||.|||.||||:.||||.|.|.||..:|..:..||||
 Frog   180 ISSSMDI-SGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNGKPCNLPGYLPPTKNGVEPK 243

  Fly   282 RPPRPVNVTSNVKLSPTVTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTR 346
            ||.||:|:||.|:||.||.|||.|.|..:..|::.|||||||:|:|..||||::.||::..|::|
 Frog   244 RPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNFSLAVYLVKQLSSAILLQRLRAKGIRNPDHSR 308

  Fly   347 GLIKEKLTEDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNC 411
            .|||||||.|.|.|||||.|:|||.||||||::.:|||:.||||||||||:||:||||:||||.|
 Frog   309 ALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRSLTCSHLQCFDATLYIQMNEKKPTWVC 373

  Fly   412 PVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSWSTPGLRSETQILD-TPSKPAQKV 475
            |||||.|.|::|:|||.|.|:|...   :|..|||..:|||||.  :||:.::.: |.|......
 Frog   374 PVCDKKAPYEHLIIDGLFMEILKCC---TDCDEIQFKEDGSWSP--MRSKKEVQEVTTSYNGVDS 433

  Fly   476 EVISDDIELISDDAKPVKRDLSPAQDEQPTSTSNSETVDLTL---SDSDDDMPLAKRRPPAKQAV 537
            ..||..:|            ...:.::|.:.....|.:|||:   ||.:::.|..||..|:....
 Frog   434 GCISSSVE------------HQVSSNQQSSKNKKVEVIDLTIDSSSDEEEEEPCPKRSCPSITPA 486

  Fly   538 ASSTSNGSGGGQR-----AYTPAQQPQQS---ESPEQQASRQSPEKQTVSEQQLQ---------- 584
            :..::.|....|.     :.||:..|..|   .:|..|..|. |...|.....||
 Frog   487 SPLSNKGMLNLQHQASPISRTPSLPPVDSTYINAPILQDYRH-PFHMTHMPYDLQGLDFFPFLSG 550

  Fly   585 QQQHEQPATAAVHASLLESLAAAVADQKHF------------QL-LDLAAVAAAAAATASSGQSQ 636
            :.||       .:.|||.:.|||.:::...            || ||....:|:::..|::|  .
 Frog   551 ENQH-------YNTSLLAAAAAAASEEPDLLHSSRFFPYTSSQLFLDQLNASASSSLPATNG--S 606

  Fly   637 NAG 639
            |:|
 Frog   607 NSG 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-10	NP_724749.1	SAP	49..83	CDD:128789	13/33 (39%)
		PINIT	171..307	CDD:291022	79/135 (59%)
		zf-MIZ	368..417	CDD:280964	37/48 (77%)
pias1	XP_002932990.1	SAP	11..45	CDD:128789	13/33 (39%)
		PINIT	136..279	CDD:373014	79/143 (55%)
		COG5222	<312..427	CDD:227547	72/119 (61%)
		SP-RING_PIAS	331..378	CDD:319704	35/46 (76%)
		SP-RING finger	334..376	CDD:319704	31/41 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	178	1.000	Domainoid score	I3491
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22953
Inparanoid	1	1.050	390	1.000	Inparanoid score	I1954
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1205949at2759
OrthoFinder	1	1.000	-	-		FOG0000526
OrthoInspector	1	1.000	-	-		otm47702
Panther	1	1.100	-	-	O	PTHR10782
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X350
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.070