Protein Alignment Su(var)2-10 and zmiz2

DIOPT Version :9

• Sequence 1: NP_724749.1
• Gene: Su(var)2-10 / 35927
• FlyBaseID: FBgn0003612
• Length: 640
• Species: Drosophila melanogaster
• Sequence 2: XP_002932592.1
• Gene: zmiz2 / 100126065
• XenbaseID: XB-GENE-999376
• Length: 904
• Species: Xenopus tropicalis
• Alignment Length: 604
• Identity: 133/604 - (22%)
• Similarity: 210/604 - (34%)
• Gaps: 181/604 - (29%)

  Fly    98 YAQSVQEQNATLQYIDPTRM-YSHIQLPPTVQPNPVGLVGSGQGVQVP---GGQMNVVGGAPFLH 158
            ||.:..:|:|........|| .|..|..|...|       .|...::.   .||.|...|..|.:
 Frog   293 YAPTTPQQSAPSPSYPTHRMQQSMSQYLPQAGP-------GGHFYKLTDQYNGQSNNFNGGNFAY 350

  Fly   159 THSINS---QLPIHPDVRLKKLAFYDVLGTLIKPSTLVPRNTQRV---QEV--PFYFTLTP---- 211
            ..::..   .:|.:|...|.        |....|.|.....|..:   |:|  ||...:.|
 Frog   351 NQTMTGPGRTMPGYPSSPLP--------GNPTPPMTPGSSATPYMSPGQDVKSPFLPDVKPPHNS 407

  Fly   212 --QQATEIASN--------RD--IRNSSKVEHAIQV-----QLRFCLVETSCDQED------CF- 252
              |..|..|::        ||  :....:::|.:.|     .||..:.:|...:.|      |:
 Frog   408 LHQSPTGTANDELRLTFPVRDGIVLEPFRLQHNLAVSNHVFHLRESVYKTLMMRPDLELQFKCYH 472

  Fly   253 ----------PPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVKL------SP---T 298
                      |.:|.|.||:                .|....|..|.||:..|      .|   :
 Frog   473 HEDRQMNTNWPCSVQVSVNS----------------TPLSIERGDNKTSHKPLYLKQVCQPGRNS 521

  Fly   299 VTNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYTRGLIKEKLT--------- 354
            :..|::...|     |:...:.||.:.:...:||.:..|.:.||::....||...:
 Frog   522 IQITVSACCC-----SHLFVLQLVHRPSVRSVLQGLIKKRLLPAEHCITKIKRNFSSGSIPGTPG 581

  Fly   355 ---EDADCEIATTMLKVSLNCPLGKMKMLLPCRASTCSHLQCFDASLYLQMNERKPTWNCPVCDK 416
               ||.   :..|.:||||.||:...::.||.|...|.|:||||...|||:|..:.||.||||:|
 Frog   582 PNGEDG---VEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQLNCERGTWRCPVCNK 643

  Fly   417 PAIYDNLVIDGYFQEVLGSSLL--KSDDTEIQLHQDGSWSTPGLRSETQILDTPSKPAQK----- 474
            .|:.:.|.:|.|   :||:.|.  .||..||.:....||....::.:|.|.:....|..|
 Frog   644 TALLEGLEVDQY---MLGTLLYIQNSDYEEITIDPTCSWKPVPVKPDTHIKEETDGPVLKRCRSL 705

  Fly   475 ---VEVISDDIELI-----------------------------------------SDDAKPVKRD 495
               ..|:.:.:|||                                         |:...|...:
 Frog   706 SPAHMVMPNVMELIAALGPSSSPFNNIQSAGSSDYANQGPGFQNPGGFSDGGFTSSNPGTPTMNE 770

  Fly   496 LSPAQDEQPTSTSNSETVDLTLSDSDDDMPLAKRRPPAKQAVASSTSNGSGGGQRAYTPAQQPQQ 560
            .:|.. ..|.|..:.....|.:.:.....|:..:.||            ||..:..:.|:|.|..
 Frog   771 FNPTA-PPPISYQSDIPSSLLVPEKAGGPPMHGQVPP------------SGRIEPTHNPSQSPHT 822

  Fly   561 ----SESPEQQASRQSPEK 575
                |:|..|...|.:|.:
 Frog   823 SNIGSQSAHQLHHRNTPRQ 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-10	NP_724749.1	SAP	49..83	CDD:128789
		PINIT	171..307	CDD:291022	35/187 (19%)
		zf-MIZ	368..417	CDD:280964	24/48 (50%)
zmiz2	XP_002932592.1	SP-RING_ZMIZ	596..643	CDD:319705	23/46 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3884
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940